HIV/AIDS and the nervous system / Peter Portegies, Joseph R. Berger.

Format:

Book

Author/Creator:

Portegies, Peter.

Contributor:

Berger, Joseph R., 1951-

Series:

Handbook of clinical neurology ; v. 85.

Handbook of clinical neurology ; 3rd ser., v. 85

Language:

English

Subjects (All):

AIDS (Disease)--Complications.

AIDS (Disease).

Nervous system--Diseases.

Nervous system.

Neurologic manifestations of general diseases.

HIV (Viruses).

Physical Description:

1 online resource (385 p.)

Place of Publication:

Edinburgh ; New York : Elsevier, 2007.

Language Note:

English

Summary:

This volume provides a comprehensive understanding of HIV/AIDS and neuro-AIDS, including a history of the disease, and an explanation of many of the conditions that can arise in afflicted patients, including opportunistic infections, central nervous system tumors, spinal cord disorders, myopathies and progressive encephalopathy, amongst others. Clinicians will gain a greater understanding of the complex mechanisms of the disease. Beginning with a basic introduction to HIV infections and Neuro-AIDS, practitioners will find useful data on advances in molecular biology, neuroepidemiolog

Contents:

Front Cover; Handbook of Clinical Neurology; HIV/Aids and the Nervous System; Copyright Page; Handbook of Clinical Neurology 3rd Series; Foreword; List of contributors; Contents; Chapter 1: Introduction to HIV infection and neuro-AIDS; 1.1. The epidemic in 2006; 1.2. Neuro-AIDS in 1985 and 2005; 1.3. What have we learned from HIV and its interaction with the nervous system?; Chapter 2: Neuroepidemiology of HIV/AIDS; 2.1.1. The origin of HIV; 2.1.3. Case definition; 2.1.4. Mode and trend of transmission of HIV; 2.1.5. Natural history of HIV infection; 2.1.6. The HAART era

2.2. Epidemiology of neurological complications of HIV infection2.2.2. Occurrence of HIV-D; 2.2.3. Progressive encephalopathy of childhood; 2.2.4. HIV-associated central nervous system lymphoma; 2.2.5. HIV and stroke risk; 2.2.6. HIV myelopathy; 2.2.8. HIV neuropathy; 2.2.9. HIV-related skeletal muscle disorders; 2.3.1. Bacteria; 2.3.2. Fungi; 2.3.3. Viruses; 2.3.4. Parasites; References; Chapter 3: HIV neurology in the developing world; 3.2. Diagnostic limitations in developing countries; 3.4.5. Less common infections (CMV, PCNSL, NHL, progressive multifocal leucoencephalopathy)

3.5. Pediatric HIV neurology3.6. Special issues in tropical settings; Chapter 4: The neuropathogenesis of HIV-1 infection; 4.2. Epidemiology of HAD in the era of HAART; 4.8. Prognostic biomarkers for HAD; 4.9. Future prospects for the neuropathogenesis of HIV-1 infection; Chapter 5: Neurological sequelae of primary HIV infection; 5.1. Introduction; 5.2. Epidemiology; 5.10. Investigations; 5.11. Pathogenesis; 5.12. Treatment; Chapter 6: AIDS dementia complex; 6.5.4. Neurophysiological investigations; 6.7. Pathogenesis; 6.8. Management; 6.8.3. Palliative management

Chapter 7: Neurocognitive assessment of persons with HIV disease7.2. General intellectual abilities; 7.4. Tests of specific ability areas; 7.4.1. Attention and speed of information processing; Further Reading; Chapter 8: HIV myelopathy; 8.2. Pathology; 8.4. Clinical manifestations; Chapter 9: Peripheral neuropathy in HIV infection; 9.2. Types of HIV neuropathy; 9.2.2. Toxic neuropathy; 9.4. Mononeuropathy multiplex; Chapter 10: Myopathy in HIV infection; 10.2. Epidemiology; 10.4. Laboratory studies; 10.6.2. Antiretroviral-related myopathy; Chapter 11: Cerebral toxoplasmosis in AIDS

11.2. The parasite11.4. Pathogenesis and pathology; 11.6.2. Imaging; 11.7. Treatment; Chapter 12: Cryptococcal infection; 12.2. Microbiology; 12.4. Pathogenesis; 12.7. Prognostic indicators; Chapter 13: Progressive multifocal leukoencephalopathy; 13.2. Molecular biology of JC virus; 13.4. Epidemiology of JC virus; 13.7. Clinical disease; Chapter 14: Other opportunistic infections of the central nervous system in AIDS; 14.1.2. Atypical mycobacteria; 14.2. Viral opportunistic infections; 14.2.1. Cytomegalovirus; 14.4. Parasitic infections; Chapter 15: Primary central nervous system lymphoma

15.4. Pathology

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

1-283-60936-3

9786613921819

0-7020-3536-X

OCLC:

811507369