Drug Delivery Strategies in Neurological Disorders: Challenges and Opportunities / edited by Awanish Mishra, Hitesh Kulhari.

Format:

Book

Contributor:

Mishra, Awanish, editor.

Kulhari, Hitesh, editor.

Series:

Medicine Series

Language:

English

Subjects (All):

Pharmacology.

Neurosciences.

Drug delivery systems.

Pharmaceutical chemistry.

Neuroscience.

Drug Delivery.

Pharmaceutics.

Local Subjects:

Pharmacology.

Neuroscience.

Drug Delivery.

Pharmaceutics.

Physical Description:

1 online resource (457 pages)

Edition:

1st ed. 2023.

Place of Publication:

Singapore : Springer Nature Singapore : Imprint: Springer, 2023.

Summary:

This book comprehensively reviews the recent progress in the pathogenesis and management approaches for neurological disorders. It focuses on understanding the molecular mechanism, pathology, and novel nanotechnology-based approaches against stroke, Alzheimer’s disease, Parkinson's disease, Huntington’s disease, Multiple sclerosis, and Epilepsy. The book provides a basic understanding of the development and progression of these diseases, and recent pharmacotherapeutic approaches for their management. It also discusses challenges in drug development for neurological disorders, including preclinical models of disorders, the need for drugs to cross the blood-brain barrier, and a limited understanding of relevant pathophysiology. The book also focuses on different conventional and novel strategies for drug delivery in neurological disorders. Towards the end, the book reviews the applications of nanotechnology for the diagnosis of neurological disorders. One of the chapters is focused on the role of herbal actives in the treatment of neurological disorders. Finally, a chapter is included on nanotechnology-based approaches for the diagnosis of neurological disorders. This book is a useful resource for students and researchers of pharmaceutical sciences, life sciences, material sciences, and nano sciences.

Contents:

Section A: Anatomy and Physiology of Human Nervous System

Chapter 1. Nanocarriers as an emerging tool for drug delivery to combat neurodegenerative diseases

Chapter 2. Challenges in drug development for neurological disorders

Chapter 3. Transporter systems and metabolism at the blood-brain barrier and blood-CSF barrier

Section B: Pathophysiology and management of Neurological disorders

Chapter 4. Pathophysiology and management approaches for Alzheimer’s Disease

Chapter 5. Pathophysiology and management approaches for Parkinson's Disease

Chapter 6 Pathophysiology and management approaches for Epilepsy

Chapter 7. Pathophysiology and management approaches for Epilepsy

Chapter 8. Pathophysiology and management approaches for Multiple Sclerosis, Huntington’s disease, and other neurodegenerative diseases

Chapter 9. Genes Encoding Ion Channels in Neurotherapeutics: Opportunities and Challenges

Chapter 10. Herbal approaches for the management of neurological disorders

Section C: Drug Delivery Strategies in Neurological disorders

Chapter 11. Essential Considerations for brain delivery of nanoformulations

Chapter 12. Drug delivery strategies in Alzheimer’s disease

Chapter 13. Drug delivery strategies in Parkinson's disease

Chapter 14. Drug delivery strategies in Epilepsy

Chapter 15. Drug delivery strategies in Traumatic Brain Injury

Chapter 16. Drug delivery strategies in Multiple Sclerosis, Huntington’s disease, and other neurodegenerative diseases

Chapter 17. Nose-to-brain strategies for neurological disorders

Chapter 18. Drug delivery strategies for the delivery of natural compounds to the brain.

Notes:

Includes bibliographical references.

Description based on publisher supplied metadata and other sources.

ISBN:

981-9968-07-0

OCLC:

1425793065