Helicobacter pylori / edited by Nayoung Kim.

Format:

Book

Contributor:

Kim, Nayoung, editor.

Series:

Medicine Series

Language:

English

Subjects (All):

Gastroenterology.

Bacteria.

Local Subjects:

Gastroenterology.

Bacteria.

Physical Description:

1 online resource (738 pages)

Edition:

2nd ed. 2023.

Place of Publication:

Singapore : Springer Nature Singapore : Imprint: Springer, 2023.

Summary:

This book presents the current state of knowledge regarding the ability of Helicobacter pylori to colonize the gastrointestinal tract, the global epidemiology of H. pylori infection, transmission routes, the pathophysiology of H. pylori-related gastroduodenal and other diseases, diagnosis and treatment methods, guidelines for eradication, antibiotic resistance, the reinfection and recrudescence rate after H. pylori eradication, the effect of H. pylori and its eradication on the gastric microbiota and animal models of H. pylori or related Helicobacter infection. The aim is to equip readers around the world with the understanding required in order to implement effective methods of H. pylori eradication and to enhance clinical outcomes for patients. In addition, readers can understand the interaction between H. pylori and other gut microbiota during chronic infection and after H. pylori eradication. The text is clearly written and is complemented by many helpful illustrations. This book will be a great asset in clinical practice for all practitioners who are involved in caring for patients with H. pylori-related diseases or have an interest in the subject. It will also be a useful source of information for medical students and for intelligent laypeople seeking information on H. pylori.

Contents:

Part I Epidemiology

1 Prevalence and Transmission Routes of H. pylori

Part II Pathophysiology

2 Gastric Colonization by H. pylori

3 Immunological Reactions on H. pylori Infection

4 Change of Acid Secretions, Ghrelin and Leptin, by H. pylori

5 H. pylori Virulence Factors: Toxins (CagA, VacA, DupA, OipA, IceA)

6 H. pylori Virulence Factors: Genetic Polymorphism and Disease

7 Host Factor: Genetic Polymorphism

Part III Diagnosis

8 Serology

9 Histopathologic Diagnosis of H. pylori Infection and Associated Gastric Diseases

10 Culture

11 Urea Breath Test

12 H. pylori Stool Antigen Test

13 Specific Conditions: Children

14 Specific Conditions: Diagnosis of H. pylori Infection in Case of Upper Gastrointestinal Bleeding

Part IV Symptom

15 Symptoms of Acute and Chronic H. pylori Infection

Part V Disease

16 Synopsis of H. pylori-Associated Diseases

17 Atrophic Gastritis and Intestinal Metaplasia

18 Functional Dyspepsia

19 Peptic Ulcer

20 Gastric Extranodal Marginal Zone B-Cell Lymphoma of MALT

21 Gastric Cancer: Synopsis and Epidemiology of Gastric Cancer

22 Gastric Cancer: Genetic Alternations Induced by H. pylori Infection: The Role of Activation- Induced Cytidine Deaminase

23 Gastric Cancer: Epigenetic Mechanisms: Aberrant DNA Methylation and Dysregulation of MicroRNA

24 Gastric Cancer: H. pylori and Macrophage Migration Inhibitory Factor

25 Gastric Cancer: Epithelial Mesenchymal Transition

26 Gastric Cancer: ABO Blood Type

27 Gastric Cancer: First Relatives of Gastric Cancer

28 H. pylori Infection-Negative Gastric Cancer

29 Gastroesophageal Reflux Disease

30 NSAID-Induced Gastropathy and H. pylori Infection

31 Extraintestinal Manifestations of H. pylori Infection: H. pylori- Associated Iron-Deficiency Anemia

32 Extraintestinal Manifestations of H. pylori Infection: Idiopathic Thrombocytopenic Purpura

33 Extraintestinal Manifestations of H. pylori Infection: Heart Disease

34 Extraintestinal Manifestations of H. pylori Infection: Asthma and Allergic Disorders

Part VI Antibiotic Resistance

35 Synopsis of Antimicrobial Resistance

36 Clarithromycin

37 Amoxicillin

38 Fluoroquinolone

39 Metronidazole

Part VII Treatment

40 Synopsis of Antibiotic Treatment

41 Triple Therapy

42 Quadruple Therapy

43 Sequential Therapy

44 Concomitant Therapy and Hybrid Therapy

45 Tailored Therapy Based on Antibiotic Resistance

46 Levofloxacin/Moxifloxacin or Rifabutin-Based Triple Therapy

47 Probiotics

48 Treatment Guidelines

49 Gastric Cancer Screening

50 Recrudescence and Reinfection After H. pylori Eradication Treatment

Part VIII Consequences of H. pylori Eradication

51 Peptic Ulcer Disease

52 Atrophic Gastritis and Intestinal Metaplasia

53 Gastric Cancer

54 Extraintestinal Manifestations Depending on Sex and Age

Part IX The Effect of H. pylori Infection and its Eradication on the Gastric Microbiota

55 The Effect of H. pylori Infection on theGastric Microbiota

56 The Effect of H. pylori Eradication on the Gastric Microbiota

Part X Animal Model

57 Animal Models of H. pylori Infection.

Notes:

Includes bibliographical references and index.

Description based on publisher supplied metadata and other sources.

ISBN:

981-9700-13-2

OCLC:

1425790642