Nanotechnology Based Delivery of Phytoconstituents and Cosmeceuticals / Deep Pooja and Hitesh Kulhari, editors.

Format:

Book

Contributor:

Pooja, Deep, editor.

Kulhari, Hitesh, editor.

Series:

Biomedical and Life Sciences Series

Language:

English

Subjects (All):

Pharmaceutical chemistry.

Nanomedicine.

Physical Description:

1 online resource (353 pages)

Edition:

First edition.

Place of Publication:

Singapore : Springer, [2024]

Summary:

This book explores the role of nanotechnology in the delivery of natural phytoconstituents and cosmeceuticals.It presents polymeric nanocarriers, lipid-based nanocarriers, metal/metal oxide nanocarriers, protein nanocarriers, and dendrimers for the delivery of phytoconstituents.

Contents:

Intro

Preface

Contents

Editors and Contributors

1: Introduction of Nanoscience and Nanotechnology

1.1 Introduction

1.2 Unique Properties of Nanomaterials and Nanostructures

1.2.1 Surface Properties

1.2.2 Optical Properties

1.2.3 Electrical Properties

1.2.4 Mechanical Properties

1.2.5 Thermal Properties

1.2.6 Magnetic Properties

1.3 Classification of Nanomaterials and Nanostructures

1.3.1 On the Basis of Dimensions

1.3.1.1 0D NMs and NSs

1.3.1.2 1D NMs and NSs

1.3.1.3 2D NMs and NSs

1.3.1.4 3D NMs and NSs

1.3.2 On the Basis of Materials

1.3.2.1 Organic NMs

1.3.2.2 Inorganic NMs

1.3.2.3 Carbon-Based NMs

1.3.3 On the Basis of Origin

1.3.3.1 Natural NMs and NSs

1.3.3.2 Anthropogenic NMs and NSs

1.3.4 On the Basis of Porosity

1.3.4.1 Microporous NMs

1.3.4.2 Mesoporous NMs

1.3.4.3 Macroporous NMs

1.3.5 On the Basis of Crystallinity

1.3.6 On the Basis of Dispersions

1.4 Synthesis of Nanomaterials and Nanostructures

1.4.1 Top-Down Approach

1.4.1.1 Mechanical Ball Milling

1.4.1.2 Sputtering

1.4.1.3 Electrospinning

1.4.1.4 Lithography

1.4.1.5 Laser Ablation

1.4.2 Bottom-Up Approach

1.4.2.1 Sol-Gel Method

1.4.2.2 Hydrothermal Method

1.4.2.3 Chemical Vapor Deposition (CVD)

1.4.2.4 Physical Vapor Deposition (PVD)

1.5 Characterization Techniques for Nanomaterials and Nanostructures

1.5.1 Microscopic Techniques

1.5.1.1 Scanning Electron Microscopy (SEM)

1.5.1.2 Transmission Electron Microscopy (TEM)

1.5.1.3 Atomic Force Microscopy (AFM)

1.5.2 Spectroscopic Techniques

1.5.2.1 UV-Visible Spectroscopy (UV-Vis)

1.5.2.2 Fourier Transform Infrared Spectroscopy (FTIR)

1.5.2.3 Nuclear Magnetic Resonance Spectroscopy (NMR)

1.5.2.4 Raman Spectroscopy (RS)

1.5.2.5 X-Ray Photoelectron Spectroscopy (XPS).

1.5.3 Thermal Techniques

1.5.3.1 Thermogravimetric Analysis (TGA)

1.5.3.2 Differential Scanning Calorimetry (DSC)

1.5.4 Dynamic Light Scattering (DLS)

1.5.5 Diffraction Technique

1.5.5.1 X-Ray Diffraction (XRD)

1.6 Applications of Nanoscience and Nanotechnology

1.6.1 Energy

1.6.2 Electronics

1.6.3 Agriculture

1.6.4 Drug and Gene delivery

1.7 Conclusion and Future Perspectives

References

2: Therapeutic Phytoconstituents-I

2.1 Introduction

2.2 Terpenes

2.2.1 Hemiterpenes

2.2.2 Monoterpenes

2.2.3 Sesquiterpenes

2.2.4 Diterpenes

2.2.5 Triterpenes

2.2.6 Tetraterpenes

2.2.7 Polyterpenes

2.3 Phenolic Compounds

2.4 Glycosides

2.5 Cyanogenic Glycosides

2.6 Alkaloids

2.7 Saponins

2.8 Conclusion

3: Therapeutic Phytoconstituents-II

3.1 Introduction

3.2 Pathophysiology of Cancer

3.3 Drugs for Cancer Treatment and Their Limitations

3.4 Anticancer Potential of Phytochemicals: A Novel Approach

3.5 Hallmarks of Cancer and Action of Phytoconstituents

3.5.1 Phytoconstituents Targeting Apoptosis

3.5.2 Phytoconstituents Affecting Angiogenesis

3.5.3 Phytoconstituents Targeting Epithelial to Mesenchymal Transition (EMT)

3.5.4 Phytoconstituents as Anti-Inflammatory Agents

3.5.5 Phytoconstituents Altering Autophagy

3.6 Seeking Innovative Methods for Using Phytochemicals Against Cancer

3.6.1 Extraction

3.6.2 Synergism

3.6.3 Nanotechnology for the Delivery of Phytoconstituents

3.7 Potential Challenges with Phytochemical-Based Anticancer Therapy

3.8 Conclusion and Future Perspective

4: Polymeric Nanocarriers for the Delivery of Phytoconstituents

4.1 Introduction

4.2 Polymeric Nanocarriers

4.3 Types of Polymers

4.3.1 Natural Polymers

4.3.1.1 Plant-Derived Polymers

Cellulose

Zein

Starch.

Soy Protein

4.3.1.2 Animal-Derived Polymers

Albumin

Hyaluronic Acid

Gelatin

4.3.1.3 Marine Organisms: Originated Polymers

Carrageenan

Agarose

Chitosan

Alginate

Fucoidan

4.3.1.4 Microorganism-Sourced Polymers

Dextran

Mauran

4.3.2 Semisynthetic Polymers

4.3.3 Synthetic Polymers

4.3.3.1 Poly(Dioxanones) (PDX)

4.3.3.2 Polyesters

4.3.3.3 Poly(Lactic-Co-Glycolide)

4.3.3.4 Poly(Lactic Acid)

4.3.3.5 Poly(2-Oxazolines)

4.3.3.6 Phosphate-Linked Polymers

4.3.3.7 Poly-β-Malic Acid

4.3.3.8 Polyanhydrides (PAs)

4.3.3.9 Poly-ε-Caprolactone (PCL)

4.4 Method of Preparation of Polymeric Nanocarriers

4.4.1 Emulsification and Solvent Extraction/Evaporation Technique

4.4.2 Emulsion Diffusion Technique

4.4.3 Nanoprecipitation Method

4.4.4 Supercritical Antisolvent Method

4.4.4.1 Salting Out

4.4.4.2 Emulsion Polymerization

4.4.4.3 Dialysis

4.5 Physicochemical Properties of Polymeric Nanocarriers

4.5.1 Particle Size

4.5.2 Particle Shape

4.5.3 Architecture of Nanocarrier

4.5.4 Particle Surface

4.5.5 Stability

4.6 Preclinical and Clinical Evidence of Phytoconstituent-Incorporated Nanocarriers for Targeted Drug Delivery

4.6.1 Polymeric Nanocarriers Loaded with Phytoconstituents for Diabetes

4.6.2 Polymeric Nanocarriers Loaded with Phytoconstituents for Neurodegenerative Disorders

4.6.3 Polymeric Nanocarriers Loaded with Phytoconstituents for the Treatment of Cancer

4.6.4 Polymeric Nanocarriers Loaded with Phytoconstituents for Ocular Drug Delivery

4.7 Conclusion and Future Perspectives

5: Lipid-Based Nanocarriers for the Delivery of Phytoconstituents

5.1 Introduction

5.2 Advantages and Disadvantages of LBNPs

5.3 Routes of Administration of LBNPs for Phytoconstituent Delivery

5.3.1 LBNPs for Topical DDS.

5.3.2 LBNPs for Oral DDS

5.3.3 LBNPs for Ocular DDS

5.3.4 LBNPs for Parenteral DDS

5.3.5 LBNPS for Pulmonary DDS

5.3.6 LBNPs for Brain DDS

5.4 Various Types/Forms of LBNPs

5.4.1 Liposome

5.4.2 Niosomes

5.4.3 Exosomes

5.4.4 Transferosomes

5.4.5 Ethosome

5.4.6 Solid Lipid Nanoparticles (SLNs)

5.4.7 Nanostructured Lipid Carriers (NLCs)

5.4.8 Nanoemulsion (NE)

5.5 Lipid-Based Nanoparticles for the Delivery of Phytoconstituent

5.5.1 Applications of LBNPs to Deliver Phytoconstituents for the Treatment of Cancer

5.5.1.1 Colorectal Cancer

5.5.1.2 Pancreatic Cancer

5.5.1.3 Liver Cancer

5.5.1.4 Prostate Cancer

5.5.1.5 Breast Cancer

5.5.1.6 Lung Cancer

5.5.1.7 Brain Cancer

5.5.2 LBNPs to Deliver Phytoconstituents for the Treatment of Neurological Disorders

5.5.3 LBNPs to Deliver Phytoconstituents for the Treatment of Psoriasis

5.5.4 LBNPs to Deliver Phytoconstituents for the Treatment of Skin Diseases

5.5.5 LBNPs to Deliver Phytoconstituents for the Treatment of Aging

5.6 Conclusion and Future Perspective

6: Supramolecule-Mediated Delivery of Phytochemicals

6.1 Introduction

6.2 Types and Structures of Supramolecules

6.2.1 Cucurbit[n]urils

6.2.2 Crown Ethers

6.2.3 Cyclodextrins

6.2.4 Calix[n]arenes

6.3 Properties of Supramolecules

6.3.1 Self-Assembly

6.3.2 Selective Molecular Recognition

6.3.3 Host-Guest Chemistry

6.3.4 Stimuli-Responsiveness

6.3.5 Hierarchical Organization

6.3.6 Solubility

6.3.7 Dynamic Properties

6.3.8 Optical and Electronic Properties

6.3.9 Biological Activity

6.3.10 Stability

6.4 Advantages and Disadvantages of Supramolecules

6.4.1 Advantage of Supramolecules

6.4.2 Disadvantages of Supramolecules

6.5 Supramolecule-Mediated Phytochemical Delivery

6.6 Conclusion

References.

7: Metal/Metal Oxide Nanocarriers for the Delivery of Phytoconstituents

7.1 Introduction

7.2 Overview of Metal and Metal Oxide Nanoparticles and Their Unique Properties

7.2.1 Gold Nanoparticles (Au NPs) Properties

7.2.2 Silver Nanoparticles (Ag NPs) Properties

7.2.3 Superparamagnetic Iron Oxide Nanoparticles (SPIONs) Properties

7.2.4 Manganese Oxide Nanoparticles (MnO-Based NPs) Properties

7.2.5 Mesoporous Silica Nanoparticles (MSNPs) Properties

7.2.6 Zinc Oxide Nanoparticles (ZnO NPs) Properties

7.2.7 Calcium Phosphate Nanoparticles (CaP NPs) Properties

7.3 General Approaches for the Preparation of Metal-Based Nanoparticles

7.4 Alteration of the Surface of Metal-Based Nanoparticles for Phytoconstituent Delivery

7.5 Role of Phytoconstituents in the Synthesis of Metal/Metal Oxide NPs

7.6 Therapeutic Phytoconstituents-Loaded Metal-Based Nanoparticles

7.6.1 Curcumin (CUR)

7.6.2 Quercetin (QUT)

7.6.3 Resveratrol (RSV)

7.6.4 (-)-Epigallocatechin-3-gallate (EGCG)

7.6.5 Morin Hydrate (MH)

7.6.6 Camptothecin (CPT)

7.7 Conclusion

8: Protein Nanocarriers for the Delivery of Phytoconstituents

8.1 Introduction

8.2 Protein Nanocarriers for the Delivery of Phytoconstituents

8.3 Types of Protein Nanocarriers Used for Delivery of Phytoconstituents

8.3.1 Albumins

8.3.2 Silk Proteins

8.3.3 Protamine

8.3.4 Gliadin

8.3.5 Legumin

8.3.6 Collagen

8.3.7 Gelatin

8.3.8 Casein

8.3.9 Zein

8.3.10 Elastin-Like Polypeptides

8.3.11 Virus-Like Particles

8.4 Methods for Preparation of Protein Nanocarriers

8.4.1 Emulsification

8.4.2 Coacervation

8.4.3 Electrospraying

8.4.4 Nanospray Drying

8.4.5 Desolvation

8.4.6 Self-Assembly

8.5 Route of Administration for Protein Nanocarriers.

8.6 Biomedical Applications of Phytoconstituents-Encapsulated Protein Nanocarriers.

Notes:

Includes bibliographical references.

Description based on publisher supplied metadata and other sources.

Description based on print version record.

Other Format:

Print version: Pooja, Deep Nanotechnology Based Delivery of Phytoconstituents and Cosmeceuticals

ISBN:

9789819953141

OCLC:

1417758860