1 option
Macrolides as Immunomodulatory Agents / edited by Bruce K. Rubin, Masaharu Shinkai.
Springer Nature - Springer Biomedical and Life Sciences eBooks 2024 English International Available online
View online- Format:
- Book
- Series:
- Progress in Inflammation Research, 2296-4525 ; 92
- Language:
- English
- Subjects (All):
- Inflammation.
- Cancer.
- Immune system.
- Cellular signal transduction.
- Immunology.
- Immunotherapy.
- Cancer Biology.
- Immune Cell Signalling.
- Local Subjects:
- Inflammation.
- Cancer Biology.
- Immune Cell Signalling.
- Immunology.
- Immunotherapy.
- Physical Description:
- 1 online resource (VIII, 287 p. 18 illus., 10 illus. in color.)
- Edition:
- 1st ed. 2024.
- Place of Publication:
- Cham : Springer International Publishing : Imprint: Springer, 2024.
- Summary:
- For over 50 years, clinicians have known that macrolide antibiotics have effects on inflammation and the immune system that are not related to their antimicrobial properties. These immunomodulatory properties, best described for treating inflammatory airway diseases, protect the lung and the host and improve clinical status. This book summarizes our current knowledge regarding proposed mechanisms for these properties, established clinical results, and what the future may hold with emphasis on novel clinical applications and the fascinating development of non-antimicrobial macrolides with preserved and enhanced immunomodulatory properties.
- Contents:
- Part I. Mechanisms of Action and Novel Macrolides
- Macrolides and Diseases Associated with Loss of Epithelial Barrier Integrity
- Macrolides and Inflammatory Cells, Signaling, and Mediators
- Part II. Clinical Use for Airway Disease
- Macrolides as Immunomodulatory Agents
- Macrolides and Cystic Fibrosis
- Non-CF Bronchiectasis
- Macrolide Use in Chronic Obstructive Pulmonary Disease
- Macrolides and Asthma Therapy
- Macrolides and Interstitial Lung Diseases
- Macrolides in Acute Respiratory Distress Syndrome and Acute Lung Injury
- Azithromycin for Other Lung Diseases: Lung Transplantation and Sarcoidosis
- Macrolides for Rhinosinusitis and Nasal Polyps
- Part III. Clinical Use for Other Diseases
- Macrolides for Cancer
- Macrolides in Chronic Skin Disorders
- Macrolide Use in Preschool Aged Children with Acute or Recurrent Respiratory Tract Illnesses with Wheezing
- Macrolides and Immunomodulation: Today and the Future.
- Notes:
- Includes bibliographical references.
- ISBN:
- 3-031-42859-5
The Penn Libraries is committed to describing library materials using current, accurate, and responsible language. If you discover outdated or inaccurate language, please fill out this feedback form to report it and suggest alternative language.