1 option
Modulating gene expression to treat diseases / Navneet Matharu.
- Format:
- Video
- Author/Creator:
- Matharu, Navneet, (University of California San Francisco, USA), Speaker.
- Series:
- Henry Stewart talks. Biomedical & life sciences collection.
- The biomedical & life sciences collection, 2056-452X
- Language:
- English
- Subjects (All):
- CRISPR (Genetics).
- Gene expression.
- Gene targeting.
- Gene therapy.
- Medical genetics.
- Molecular genetics.
- Basic Helix-Loop-Helix Proteins.
- Clustered Regularly Interspaced Short Palindromic Repeats.
- CRISPR-Cas Systems.
- Gene Expression Regulation.
- Gene Targeting--methods.
- Genetic Diseases, Inborn--therapy.
- Haploinsufficiency.
- Loss of Function Mutation.
- Obesity--genetics.
- Obesity--therapy.
- Receptor, Melanocortin, Type 4.
- Repressor Proteins.
- Up-Regulation.
- Medical Subjects:
- Basic Helix-Loop-Helix Proteins.
- Clustered Regularly Interspaced Short Palindromic Repeats.
- CRISPR-Cas Systems.
- Gene Expression Regulation.
- Gene Targeting--methods.
- Genetic Diseases, Inborn--therapy.
- Haploinsufficiency.
- Loss of Function Mutation.
- Obesity--genetics.
- Obesity--therapy.
- Receptor, Melanocortin, Type 4.
- Repressor Proteins.
- Up-Regulation.
- Physical Description:
- 1 online resource (1 streaming video file (20 min.)) : sound, color
- Place of Publication:
- London : Henry Stewart Talks, 2021.
- System Details:
- video file
- Contents:
- Contents: Programmable DNA targeting modules
- Effector domain functions and possibilities
- Haploinsufficiency and its role in disease
- CRISPRa targeting strategy to rescue Sim1 obesity
- CRISPRa targeting strategy to treat Mc4r haploinsufficiency.
- Notes:
- Description based on publisher supplied metadata and other sources.
- Animated audio-visual presentation with synchronized narration.
- Title from title frames.
- Publisher Number:
- 5594 Henry Stewart Talks
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