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Tolerance induction to clotting factors with monoclonal antibodies / Luís Graça.
- Format:
- Video
- Author/Creator:
- Graça, Luís (University of Lisbon, Portugal), Speaker.
- Series:
- Henry Stewart talks. Biomedical & life sciences collection. Monoclonal antibodies as therapeutic agents : fundamentals, therapeutic applications and latest advances.
- Monoclonal antibodies as therapeutic agents : fundamentals, therapeutic applications and latest advances, 2056-452X
- Language:
- English
- Subjects (All):
- Hemophilia--Immunological aspects.
- Hemophilia.
- Hemophilia--Treatment.
- Immunological tolerance.
- Monoclonal antibodies.
- Adjuvants, Immunologic--pharmacology.
- Antibodies, Monoclonal--administration & dosage.
- Antigen Presentation.
- Blood Coagulation Factors.
- Forkhead Transcription Factors.
- Hemophilia A--drug therapy.
- Hemophilia A--immunology.
- Immune Tolerance--drug effects.
- Interleukin-10.
- Lymphocyte Depletion.
- T-Lymphocytes, Regulatory.
- Medical Subjects:
- Adjuvants, Immunologic--pharmacology.
- Antibodies, Monoclonal--administration & dosage.
- Antigen Presentation.
- Blood Coagulation Factors.
- Forkhead Transcription Factors.
- Hemophilia A--drug therapy.
- Hemophilia A--immunology.
- Immune Tolerance--drug effects.
- Interleukin-10.
- Lymphocyte Depletion.
- T-Lymphocytes, Regulatory.
- Physical Description:
- 1 videorecording (30 min., 16 sec.) : sound, color.
- Place of Publication:
- London : Henry Stewart Talks, 2020.
- System Details:
- video file
- Contents:
- Contents: The immunogenicity of foreign tissues and proteins
- Induction of immune tolerance with monoclonal antibodies
- Properties of therapeutic immune tolerance
- The challenges to achieve tolerance to clotting factors in hemophilia
- The importance of appropriate antigen presentation for effective immune tolerance induction
- Cellular and molecular mechanisms underlying immune tolerance: IL-10, Foxp3, regulatory T cells, and T cell depletion
- Different routes of antigen presentation can recruit different tolerance mechanisms.
- Notes:
- Animated audio-visual presentation with synchronized narration.
- Title from title frames.
- Publisher Number:
- 5197 Henry Stewart Talks
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