Recognition of 'self' and 'non-self' glycans by carbohydrate-binding proteins : structural and functional aspects / Gerardo R. Vasta.

Format:

Video

Author/Creator:

Vasta, Gerardo R., author.

Language:

English

Subjects (All):

Polysaccharides.

Physical Description:

1 online resource (1 streaming video file (31 min.)) : color, sound

Other Title:

Recognition of 'self' and 'non-self' glycans by carbohydrate-binding proteins

Place of Publication:

London : Henry Stewart Talks Ltd, 2012.

System Details:

video file

Contents:

Introduction

Recognition of cell surface and soluble glycans

Hallmarks of innate and adaptive immunity

Innate immune receptors (1)

Domain structure of lectin subunits

Classification of animal lectins

Lectin families

C- type lectins

The mammalian MBL

Direct recognition of microbes / opsonic effect

Activation of complement pathways

Lectin repertories in self and nonself recognition

MsFBP-32 in Morone saxatilis

Topology of F-type lectin family (1)

Structure of the eel lectin subunit and trimer

Interactions of binding sites with ligands

Modeling of Le-a and H blood group specificity

Topology of F-type lectin family (2)

Structure of a binary CRD lectin (MsFBP32) (1)

Structure of a binary CRD lectin (MsFBP32) (2)

Structure of a binary CRD lectin (MsFBP32) (3)

Structure of a binary CRD lectin (MsFBP32) (4)

Trimeric CRD displays in F-lectins

Sequence variability among eel isolectins

Glycan recognition by F-type eel lectin isoforms

Topology of F-type lectin family (3)

Bindin: F-lectin involved in fertilization

Topology of F-type lectin family (4)

Discoidin II

Self and nonself recognition by F-type lectins

Structural and functional diversity of F-lectins

Galectins

Biological roles of galectins (1)

Zebrafish galectin repertoire

Drgal1-L2 is strongly expressed in the notochord

Skeletal muscle in Drgal1-L2/Drgal1-L4

Zebrafish Drgal1-L2

Biological roles of galectins (2)

Biological roles of galectins (3)

Galectins recognize glycans on many pathogens

Innate immune receptors (2)

Oysters are efficient filter feeders

Ultrastructure of Perkinsus sp.

Phagocytosis of P. marinus trophozoites

A 4-CRD galectin in Crassostrea virginica

Properties of rCvGal

CvGal location in granulocytes upon attachment

Anti-rCvGal antibodies inhibit phagocytosis

Subversion of host galectins by parasites

Galectins as PRRs

Acknowledgments.

Notes:

Description based on publisher supplied metadata and other sources.

Retrieved April 15, 2024, from https://hstalks.com/bs/2427/.