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Transcription elongation control by RNA polymerase II / Dr. Ali Shilatifard.

Henry Stewart Biomedical & Life Sciences Collection Available online

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Format:
Video
Author/Creator:
Shilatifard, Ali, author.
Series:
Henry Stewart talks
Language:
English
Subjects (All):
Genetic transcription.
Physical Description:
1 videorecording (45 min., 57 sec.) : sound, color.
Place of Publication:
London : Henry Stewart Talks Ltd, [2007]
System Details:
video file
Summary:
Audio-visual presentation : Transcriptional elongation ; Complexes involved ; Mechanisms regulating rate and efficiency of elongation on chromatin templates.
Contents:
Intro slide
Regulation of gene expression by RNA pol ll
The basal transcription machinery
The initiation and elongation factors
The process of transcription cycle
The rate of transcription elongation
Different classes of RNA pol ll elongation factors
Factors increasing the rate of transcribing RNA pol
Factors assisting through transient pausing sites
Factors assisting to transcribe through chromatin
Factors without biochemical activities
Factors increasing transcription rate of RNA pol. II
ELL increase the catalytic rate of elongation
MLL and ELL chimera
Immortalization of primary progenitor cells
The results of immortalization experiment
ELL - summary
The elongin complex
In vivo properties of elongin A
Reduction of elongin A
dEloA is required for the transition to adulthood
dEloA re-localizes upon heat shock
dEloA is required for heat shock gene expression
Elongin A - summary
The role of COMPASS in methylation of histones
Set1 is essential for the methylation of histone H3
Microplate of viable yeast deletion mutants
GPS in S.cerevisiae (1)
GPS in S.cerevisiae (2)
RAD6 is essential for methylation of histone H3
The role of E3 in substrate specificity
Bre1 identified as E3-ligase
COMPASS association with transcribed region
Paf1 complex role in methylation by COMPASS
The model (1)
The model (2)
Transcriptional memory
The role of RNA pol ll elongation factors
Future studies.
Notes:
Description based on publisher supplied metadata and other sources.
Retrieved April 8, 2024, from https://hstalks.com/bs/661/.

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