Molecular brain imaging (PET) in diseases with dementia / Prof. Karl Herholz.

Format:

Video

Author/Creator:

Herholz, Karl, author.

Series:

Henry Stewart talks

Language:

English

Subjects (All):

Brain--Diseases--Diagnosis.

Brain.

Physical Description:

1 videorecording (21 min., 32 sec.) : sound, color.

Other Title:

Molecular brain imaging

Place of Publication:

London : Henry Stewart Talks Ltd, [2020]

System Details:

video file

Contents:

Introduction

Positron-Emission-Tomography (PET)

Scope of Brain PET

FDG-PET: Normal cerebral glucose metabolism

Frequent neurodegenerative diseases with characteristic FDG PET findings

Imaging of local brain function

FDG-PET: Progression of early-onset Alzheimer's disease (AD)

Automatic detection of abnormal metabolism and regions that are typically affected by AD

Accuracy of FDG PET: diagnosis of probable AD

Posterior cingulate cortex (PCC) impairment in Alzheimer's disease

Posterior cingulate cortex (PCC)

Regional correlations (within left hemisphere)

Comparison of CMRGlc reduction due to age and AD

Frontal brain areas show reduced glucose metabolism in depression

Progressive prosopagnosia

Anosognosia in AD: metabolic changes related to patients' self assessment

Scope of brain PET

High-affinity amyloid PET tracers

Imaging cerebral amyloid

18F-florbetapir: loss of g/w contrast as diagnostic criterion for amyloid deposition

Amyloid pathology and resilience to AD

Tau PET (18F-AV-1451)

Frontotemporal lobar atrophies

Genetics and pathology

Fronto-temporal dementia with Amyotrophic Lateral Sclerosis

Frontotemporal dementia and asymmetric frontotemporal atrophy

Tracers for the dopaminergic system

Anatomy of the dopaminergic system

Mild Parkinson's disease (HY2)

Striatonigral degeneration (SD) compared to Parkinson's disease (PD)

Progressive supranuclear palsy

Chorea Huntington

FDG PET metabolic signatures

Cholinergic systems

PET-tracers for the cholinergic system

AChE activity measured by C-11-MP4A

Dementia with Lewy Bodies (DLB)

Transmitter deficits in Lewy body dementia:

Cholinergic vs. dopaminergic deficit in Parkinson's disease and Dementia with Lewy bodies (DLB)

Systems impairment in degenerative dementia

Clinical PET tracers for neurodegenerative diseases.

Notes:

Description based on publisher supplied metadata and other sources.

Retrieved April 10, 2024, from https://hstalks.com/bs/223/.