Stem cell therapy for the treatment of heart failure / Dr. James Willerson - University of Texas Health Science Center at Houston, USA.

Format:

Video

Author/Creator:

Willerson, James T., 1939-2020, author.

Language:

English

Subjects (All):

Heart failure.

Regenerative medicine.

Physical Description:

1 videorecording (38 mins., 32 sec.) : sound, color

Place of Publication:

London, England : Henry Stewart Talks Ltd, 2007.

System Details:

video file

Contents:

Introduction

Heart failure: the problem

Hospitalization and Congestive Heart Failure (CHF)

Heart failure hospitalizations

The predominant contributor to heart failure costs

Mortality in heart failure trials

Reasons for increased heart failure

Process of heart failure progression

Cycle of heart failure progression

Medical therapies for heart failure

Current treatment of CHF with systolic dysfunction

Number of heart transplants worldwide

FDA indications for LVAD usage

Stem cells in the future treatment of heart failure

Stem cells

CD34 positive stem cells

CD34+ cells differentiation into cardiomyocytes

Repair of infarcted myocardium by stem cells

Procedure of cells transplantation

Improvement in myocardial perfusion

Transplantation of progenitor cells

Assay of the left ventricular function

Evaluation of wall motion

Autologous of bone marrow cell transplantation

The NOGA myostar injection catheter

Injection catheter technique

SPECT and electromechanical map analysis

Hemodynamic data summary

Angiographic and EMM results

Infarct remodeling after progenitor cell treatment

Ejection fraction and end diastolic volume

Initial and follow-up results in endsystolic volumes

Intracoronary autologous bone marrow cell transfer

Global LVEF at baseline and 6 months follow-up

Subgroup analysis of global LVEF changes

Comparison of SMs and CD133+ progenitors

LVEF ejection fraction

Emax comparison

Transendocardial injection of ABMM

Number of capillaries

Trichrome stain of the heart walls

Improved exercise capacity and ischemia

MSCs differentiate into endothelial phenotype

Ejection fraction at rest and with stress

Fibrosis and vascular density comparison

Dil staining of the anterior and posterior walls

Stem cells in the treatment of heart disease

Use of mouse ESC to infarcted sheep myocardium

CD133+ cells enhance myocardium function

Embryonic versus adult stem cells

Conclusions

Texas heart institute.

Notes:

Description based on: online resource; title from PDF information screen (Henry Stewart Talks Biomedical and Life Sciences Collection, viewed April 5, 2024).

Retrieved April 12, 2024, from https://hstalks.com/bs/242/.