VEGF family / Kari Alitalo.

Format:

Video

Author/Creator:

Alitalo, Kari, author.

Language:

English

Subjects (All):

Neovascularization.

Cellular signal transduction.

Physical Description:

1 online resource (1 streaming video file (36 min.)) : sound, color

Place of Publication:

London : Henry Stewart Talks Ltd, 2007.

System Details:

video file

Contents:

Introduction

Tumor angiogenesis

Tumor metastasis

Vascular vs. lymphatic system

Capillary ultrastructure

Immunostained blood and lymphatic vessels

Differences between BEC and LEC

VEGF and VEGFR tyrosine kinase

VEGFR - 1, 2 and 3

Schematic structure of VEGF

What is VEGF?

VEGF family tree

Signaling via receptor tyrosine kinase (1)

Signaling via receptor tyrosine kinase (2)

Role of VEGFR-1 in angiogenesis

Biological role of VEGF

VEGF in embryonic angiogenesis

VEGF in angiogenesis during development

Physiological angiogenesis in the adult

VEGFR-4

VEGF-C role in development of lymphatics

Embryonic formation of the lymphatic vasculature

Tumor growth and angiogenesis

Tumor angiogenesis by vascular sprouting

VEGF promotes tumor angiogenic switch

Angiogenesis role in tumor progression

Tumor characteristics promote VEGF expression

Tumor hypoxia induce VEGF expression

VEGF overexpression and abnormal vasculature

Abnormal blood vessel organization in tumors

Abnormal tumor vasculature

Normal vs. tumor vasculature

VEGF induces increased permeability

VEGF makes tumor blood vessels leaky.

Notes:

Description based on publisher supplied metadata and other sources.

Retrieved April 12, 2024, from https://hstalks.com/bs/452/.