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P53 family : function and molecular mechanisms / Gerry Melino.

Henry Stewart Biomedical & Life Sciences Collection Available online

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Format:
Video
Author/Creator:
Melino, Gerry, author.
Language:
English
Subjects (All):
Apoptosis--Periodicals.
Apoptosis.
Cell death.
Physical Description:
1 videorecording (46 min., 29 sec.)
Other Title:
P53 family
Place of Publication:
London : Henry Stewart Talks Ltd, 2007.
System Details:
video file
Contents:
Introduction
Odysseus Is Tempted by the Sirens
Role and importance of p53
The p53 family (1)
The p53 family (2)
The p53 gene
p73-/- show neural defects
p73 regulates neural differentiation
p73 in immunity (1)
p73 in immunity (2)
p73 in immunity and cancer
Incidence of p73 alterations in cancer
Involvement of p73 in DNA damage response
Cell cycle arrest and apoptosis by p53 and TAp73
TAp73 induces apoptosis, while DNp73 inhibits it
The identification of p73 pathway
p73 post-translational modifications
The various proteins involved in p73 pathway
Interacting proteins: WW proteins
Role of chemo / radiotherapy in p73 activation (1)
Example: transactivation of CD95 gene (1)
p73 synergize with chemotherapy
p73 in hepatoma cells
Example: transactivation of CD95 gene (2)
Inactivation of p73 in cancer
Interaction between p53 and p63/p73
The life of a cell
Underground map of cell city
Suicide bomb attack to cancer city
Role of chemo / radiotherapy in p73 activation (2)
TAp73 degradation (1)
TAp73 degradation (2)
Degradation of ITCH and DNp73 in DNA damage
Can we control p73 protein levels?
Role of PML in stabilizing TAp73 protein
Conclusion of p73 degradation
Interacting proteins:Bub1, Bub3
p73 in cell cycle control
Summary: p73
The p53 family (3)
Some effects of p63
TAp63 induces cell cycle arrest and apoptosis
p63-induced apoptosis and p63 degradation (1)
p63-induced apoptosis and p63 degradation (2)
Role of p63 in epidermis and human diseases (1)
Role of p63 in epidermis and human diseases (2)
Vibrissae
Tooth development and p63 (1)
Tooth development and p63 (2)
Tooth development and p63 (3)
Formation of the epidermis (1)
Formation of the epidermis (2)
What is the function of p63?
p63 Transcriptional targets
Summary: p63
Evolution of the p53 family
Timescale of p63/p73 research.
Notes:
Description based on: online resource; title from PDF information screen (Henry Stewart Talks Business & Management Collection, viewed April 11, 2024).
Retrieved April 11, 2024, from https://hstalks.com/bs/292/.

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