Sodium-calcium exchange / John P. Reeves.

Format:

Video

Author/Creator:

Reeves, John P., author.

Language:

English

Subjects (All):

Calcium--Physiological effect.

Calcium.

Calcium in the body.

Physical Description:

1 videorecording (44 min., 29 sec.)

Place of Publication:

London : Henry Stewart Talks Ltd, 2007.

System Details:

video file

Summary:

Audio-visual presentation : The definition and thermodynamic driving forces for Na/Ca exchange and the historical development of the field ; The molecular biology of Na/Ca exchange family members ; The regulation of Na/Ca exchange ; The physiological functions of Na/Ca exchange in cardiac physiology, hypertension and higher neural functions.

Contents:

Introduction

Na/Ca exchange (NCX) - overview

NCX and Ca homeostasis

Energetics of Na/Ca exchange

NCX is bi-directional

K-dependent Na/Ca exchange: NCKX

A brief history of Na/Ca exchange

NCX exchanger families

NCX1 protein

Splice variants of NCX1

Helix packing of NCX1

Consecutive reaction mechanism

Overview of NCX regulation

PIP2 blocks Na-dependent inactivation

PIP2 interacts with XIP

Regulatory Ca binding sites

Persistent Ca activation

Anomalous Ca regulation in drosophila

Squid axon Na/Ca exchanger

NCX and cardiac myocyte physiology

Cytosolic Na and cardiac contractility

NCX expression studies

NCX and cardiac pathophysiology

NCX inhibitors

NCX and hypertension?

Higher order NCX functions.

Notes:

Description based on: online resource; title from PDF information screen (Henry Stewart Talks Business & Management Collection, viewed April 11, 2024).

Retrieved April 11, 2024, from https://hstalks.com/bs/411/.