Poxviruses : smallpox (variola), vaccinia and monkeypox / Paula Traktman.

Format:

Video

Author/Creator:

Traktman, Paula, author.

Language:

English

Subjects (All):

World health.

Physical Description:

1 videorecording (1 hr., 00 min., 22 sec.)

Other Title:

Poxviruses

Place of Publication:

London : Henry Stewart Talks Ltd, 2007.

System Details:

video file

Summary:

Audio-visual presentation : Poxvirus life cycle: chromosome structure, virion structure and virion entry ; Viral proteins needed for entry and mechanism of entry of EV (enveloped virion) ; Gene expression of EV: early transcription, intermediate and late transcription ; Working model of Poxvirus genome replication ; Morphogenesis of EV ; Key features of the IV to MV (mature virions) transition ; Poxviruses encode a three-protein complex that generates disulfide bonds in the cytoplasm ; Formation of EEV (extracellular enveloped virions) and EV mediators of cell-to-cell and distal spread ; Poxviruses encode a large array of immunomodulators ; Models for the study of Poxvirus pathogenesis ; Smallpox (Variola virus) and smallpox disease ; Pathogenicity of Variola virus vs. Vaccinia virus ; Official declaration of the eradication of smallpox ; Monkeypox virus ; Antiviral therapy and new vaccines for Poxviruses.

Contents:

Introduction Topics to be covered Rationales for the study of Poxviruses Poxvirus taxonomy Poxvirus life cycle Chromosome organization The terminal region of the chromosome Virion structure Virus entry Viral proteins needed for entry Mechanism of EV entry Gene expression Temporal profile of gene expression Early gene transcription Intermediate and late gene transcription Working model of DNA replication The Poxvirus replication apparatus Schematic of the core replication apparatus Intracellular localization of genome replication Schematic of Poxvirus morphogenesis EM image of Poxvirus morphogenesis Key features of early morphogenesis Visualization of the D13 lattice Key features of the IV to MV transition Poxvirus-mediated disulfide bond formation Formation of extracellular virions Vaccinia virus egress Mechanism of EV release and spread Cytopathic effects of Orthopoxvirus infection Repertoire of Poxvirus immunomodulators Immunomodulators and disease Animal models of Poxvirus infection Smallpox - epidemiology Smallpox disease Vaccinia vs. Variola Poxvirus vaccination WHO smallpox recognition card Declaration of smallpox eradication Monkeypoxvirus Antipoxvirus therapy Rationale for the experimental study of Poxviruses Figure citations.

Notes:

Description based on: online resource; title from PDF information screen (Henry Stewart Talks Business & Management Collection, viewed April 16, 2024).

Retrieved April 16, 2024, from https://hstalks.com/bs/364/.