Statistical tests for association / Andrew P. Morris.

Format:

Video

Author/Creator:

Morris, Andrew P., author.

Language:

English

Subjects (All):

Medical genetics.

Genetic counseling.

Physical Description:

1 videorecording (34 min., 32 sec.)

Place of Publication:

London : Henry Stewart Talks Ltd, 2008.

System Details:

video file

Summary:

Audio-visual presentation: Simple contingency table tests: genotypic test and Cochran-Armitage trend test -- Logistic regression model for binary (case-control) data: incorporating covariates and extension to allow for multi-locus effects and interactions -- Quantitative trait association analysis -- Haplotype analysis: allowing for phase uncertainty in logistic regression model and methods for haplotype clustering -- Software: statistical tests of association, genome-wide association analysis and haplotype analysis.

Contents:

Introduction

Introduction to statistical tests for association

Lecture outline

Single-locus tests of association (1)

Single-locus tests of association (2)

Single-locus Cochran-Armitage trend tests

Interpretation of test results

Logistic regression model

Trend test of association

Genotypic test of association

General disease models

Allowing for covariates

Example

Quantitative traits

Multi-locus models

Multi-locus trend model of association

Software for whole genome association analysis

Haplotype association with disease

Modelling haplotype effects

Unknown phase

Allowing for unknown phase

Parsimony issues

Haplotype evolution

Haplotype clustering

Software for haplotype analysis

When is haplotype analysis appropriate?

References.

Notes:

Description based on: online resource; title from PDF information screen (Henry Stewart Talks Business & Management Collection, viewed April 8, 2024).

Retrieved April 9, 2024, from https://hstalks.com/bs/869/.