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Physiology and pathophysiology of microglia / Prof. Dr. Uwe-Karsten Hanisch.
- Format:
- Video
- Author/Creator:
- Hanisch, Prof. Dr. Uwe-Karsten, author.
- Language:
- English
- Subjects (All):
- Microglia.
- Physical Description:
- 1 videorecording (41 min., 20 sec.)
- Place of Publication:
- London : Henry Stewart Talks Ltd, 2012.
- System Details:
- video file
- Contents:
- Introduction
- Microglia: a short definition
- Microglia: resident innate immune cells of CNS
- Discovery and detection
- Discovery, detection
- functional interpretation (1)
- functional interpretation (2)
- Approaches to the study of microglia
- Manipulating and monitoring microglial activities
- Developmental origin and functions
- Microglia as macrophage-like cells
- Origin and lineage
- Developmental contributions of malfunction (1)
- Developmental contributions of malfunction (2)
- Developmental contributions of malfunction (3)
- The concept of resting microglia
- Resting or active: dormant or functional
- Tissue surveillance and synaptic nursing
- Immunologically silent disposal of myelin
- The concept of microglial activation
- Immediate response to homeostatic disturbance
- The concept of detrimental microglia
- Microglial activation simply follows a stereotype
- Microglial activation in CNS pathologies
- Harmful microglial engagement is recognized
- Activation signals and response diversity
- Microglia as active sensors
- Activity-controlling factors (1)
- Activity-controlling factors (2)
- Control via ON and OFF signals
- Microglial response versatility
- Macrophages and microglia
- Signals and response modifiers
- Elements of the microglial response repertoire (1)
- Elements of the microglial response repertoire (2)
- Response dynamics
- Microglia activation: not a monophasic response
- Microglia activation: deescalation
- termination
- Contributions in and to CNS pathologies
- Phenotypes associated with phagocytosis
- Effects associated with phagocytosis
- Microglial neuropathology in Alzheimer's disease
- Microglia in neurodegenerative diseases
- A uniform population throughout the CNS or not?
- Conclusion and outlook
- Questions regarding roles in health and disease
- Thank you.
- Notes:
- Description based on publisher supplied metadata and other sources.
- Retrieved April 13, 2024, from https://hstalks.com/bs/2355/.
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