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Oxidative stress in COPD / by Prof. William MacNee.

Henry Stewart Biomedical & Life Sciences Collection Available online

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Format:
Video
Author/Creator:
MacNee, William, author.
Language:
English
Subjects (All):
Lungs--Diseases, Obstructive--Pathophysiology.
Lungs.
Oxidative stress.
Physical Description:
1 videorecording (34 min., 10 sec.) : sound, color
Place of Publication:
London : Henry Stewart Talks Ltd, 2012.
System Details:
video file
Contents:
Introduction
Oxidants and antioxidant balance in the lungs
Oxidants and antioxidants in the lungs
Oxidative stress in COPD overview (1)
Measurements of oxidative stress
Synthesis of nitric oxide (NO)
Nitrosative stress in COPD
Mechanisms of membrane lipid peroxidation
4-hydroxy-2-nonenal-adducts in COPD
Does oxidative stress occur in COPD?
Smoke induced emphysema in Nrf2 KO mice
Decline in NRF2-regulated antioxidants in COPD
Nrf2 and oxidative stress relationship in COPD
Regulation of NRF2 in COPD patients
NRF2 targeting with CDDO
What are the consequences of OS in COPD?
Model of histone acetylation and deacetylation
Effect of smoking and COPD on HDAC2
Nitration and HDAC2 activity
Smoke induced oxidative stress effects
Emphysema: apoptosis
Apoptosis and VEGF in emphysematous lungs
Apoptosis and oxidative stress
Decreased proteins in lungs of COPD patients
Molecular alterations in COPD lungs
Molecular alterations in COPD muscles
Protease / antiprotease
NRF2 way of protection against emphysema
NAC attenuates elastase-induced emphysema
Accelerated aging
Free radical theory of aging or senescence
Accelerated aging in COPD
SIRT-1 is decreased in the lungs in COPD
SMP-30 and age-associated deterioration
Effects of decreased SIRT1
Pathogenic triad of COPD
Mucus hypersecretion
Oxidants and mucin production
Airway remodelling
A link between oxidative injury and fibrosclerosis
Immune modulation
The nature of small-airway obstruction in COPD
HO1 prevents smoke induced B-cell infiltrates
Oxidative stress role in auto-immune response
Oxidative stress in COPD: summary.
Notes:
Description based on publisher supplied metadata and other sources.
Retrieved April 12, 2024, from https://hstalks.com/bs/2364/.

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