Y-chromosome / Mark A. Jobling.

Format:

Video

Author/Creator:

Jobling, Mark A., author.

Language:

English

Subjects (All):

Human genetics.

Molecular genetics.

Physical Description:

1 online resource1 videorecording (42 min., 10 sec.)

Place of Publication:

London : Henry Stewart Talks Ltd, 2009.

System Details:

video file

Contents:

Introduction Chromosomes of a human male: 46,XY The Y chromosome is dominantly sex-determining Ovary or testis? Specialized for sex The human sex chromosomes Evolution of the sex chromosomes Pseudoautosomal region 1 (PAR1) XY pairing in pachytene A gradient of recombination in PAR1 Pseudoautosomal region 2 Sex-chromosomal recombination Identifying the testis-determining factor Translocation XX males and XY females Principle of deletion mapping the TDF interval Sex-determining region Y (SRY) Evidence that SRY is TDF Randy the transgenic mouse The SRY gene and protein The sex-determining pathway downstream of SRY Turner syndrome Turner syndrome (45,X) phenotype Turner syndrome and X-linked genes Turner syndrome - candidate genes XY-homology Y-chromosomal aneuploidies A high mutation rate on the Y The weird genomic landscape of the Y Y-linked inheritance Other Y-associated phenotypes? Y-linked deafness (DFNY1) The human Y carries fertility factors Testis histologies in normal and infertile males Finding AZF candidate genes AZF phenotypes and candidate genes Genomic disorders NAHR in AZFa and AZFc infertility The 'hall of mirrors' Complex structural rearrangements Substrates for gene conversion Gene conversion is biased 'Genetic coherence' of the Y PAR1 shows no 'genetic coherence' A single ancestor for the Y Genome segments and effective population sizes Y haplogroup distribution Applications of Y diversity Thanks.

Notes:

Description based on: online resource; title from PDF information screen (Henry Stewart Talks Business & Management Collection, viewed April 12, 2024).

Retrieved April 12, 2024, from https://hstalks.com/bs/1566/.