The Proteomic revolution / Larry Gold.

Format:

Video

Author/Creator:

Gold, Larry, author.

Language:

English

Subjects (All):

Biochemical markers.

Physical Description:

1 online resource

Place of Publication:

London, England : Henry Stewart Talks Ltd, 2022.

System Details:

video file

Contents:

Introduction

Understanding genotype to predict phenotype

The path from genotype to phenotype

A better understanding of phenotype is required

Medicine has always been "personalized"

The "omics" (molecules) we should measure

Proteomics

A technology to address the proteome complexity

SomaLogic's version of SELEX - SOMAmers

The privileged 5 position of pyrimidines

"Pull downs" show SOMAmer specificity

Crystal structures (1)

Crystal structures (2)

Crystal structures (3)

Crystal structures (4)

SOMAscan proteomic assay- from protein to DNA

SOMAmers are measured by DNA techniques

SOMAscan today

Using SOMAscan (lung cancer)

Using SOMAscan (non-small cell lung cancer)

Lung cancer serum biomarkers

Diagnostic performance of 7-marker classifier

Using SOMAscan (cardiovascular risk)

Using SOMAscan (pre-term birth)

Using SOMAscan (pancreatic cancer)

Using SOMAscan (Mesothelioma)

Using SOMAscan - diagnostic pipeline

Future goals-wellness chip, longitudinal monitoring

Longitudinal blood tests can detect cancer early

Longitudinal blood tests can facilitate Wellness

Conclusions

One last thought

Acknowledgements.

Notes:

Description based on publisher supplied metadata and other sources.

Retrieved April 15, 2024, from https://hstalks.com/bs/2394/.