War against extensively drug resistant Mycobacterium tuberculosis : intelligence acquisition / William R. Jacobs.

Format:

Video

Author/Creator:

Jacobs, William R., author.

Language:

English

Subjects (All):

Bacterial diseases.

Pathogenic bacteria.

Physical Description:

1 videorecording (42 min., 19 sec.)

Other Title:

War against extensively drug resistant Mycobacterium tuberculosis

Place of Publication:

London : Henry Stewart Talks Ltd, 2009.

System Details:

video file

Contents:

Introduction

Tuberculosis (TB) today

TB and HIV epidemic in South Africa

XDR-TB in Tugela Ferry

Patients co-infected with TB and HIV in rural SA

Susceptibility pattern of isolates from Tugela Ferry

Tugela Ferry

Hospital acquired XDR-TB (1)

Hospital acquired XDR-TB (2)

XDR-TB realities

XDR-TB spread in KwaZulu-Natal 2005-2007

TB sanatorium evolution

The war on XDR-TB - clinical needs

M. tuberculosis knowledge - 1985 (1)

Why is knowledge important?

The causes for TB - 1847

Causes of consumption - therapy

Edward Livingston Trudeau (1)

Edward Livingston Trudeau (2)

Jean Antoine Villemin

Gerhard Armauer Hansen

Koch's postulate

M. tuberculosis knowledge - 1985 (2)

Molecular Koch's postulate

First fulfillment of molecular Koch's postulate

Why no genetics for M. tuberculosis?

Leprosy

Mycobacteriophage delivery vectors (1)

Mycobacteriophage delivery vectors (2)

fadD knockout strains

Genetics = new knowledge

Bacille Calmette and Guerin (BCG)

Why is BCG attenuated?

Molecular Koch's postulate: application to BCG

Reconstruction of BCG

The loss of RD1 attenuates MTB

Primary attenuation of BCG

Mechanism of action of INH and ETH in M. tb

How tuberculosis may develop drug resistance

InhA is the target of INH and ETH

Common target of Isoniazid and Ethionamide

Conclusions.

Notes:

Description based on: online resource; title from PDF information screen (Henry Stewart Talks Business & Management Collection, viewed April 12, 2024).

Retrieved April 12, 2024, from https://hstalks.com/bs/1478/.