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RNAi for neurological diseases / Beverly L. Davidson.
- Format:
- Video
- Author/Creator:
- Davidson, Beverly L., (University of Pennsylvania, Philadelphia.), Speaker.
- Series:
- Henry Stewart talks. Biomedical & life sciences collection. Gene transfer and gene therapy.
- Henry Stewart talks. Biomedical & life sciences collection. RNA interference : principles and applications.
- Gene transfer and gene therapy, 2056-452X
- RNA interference : principles and applications, 2056-452X
- Language:
- English
- Subjects (All):
- Gene therapy.
- Genetic vectors--Therapeutic use.
- Genetic vectors.
- Huntington's disease.
- Nervous system--Diseases--Gene therapy.
- Nervous system.
- Nervous system--Diseases--Genetic aspects.
- Small interfering RNA--Therapeutic use.
- Small interfering RNA.
- Gene Transfer Techniques.
- Genetic Therapy--methods.
- Genetic Vectors--therapeutic use.
- Huntington Disease--therapy.
- MicroRNAs--therapeutic use.
- Nervous System Diseases--therapy.
- RNA Interference.
- RNA, Small Interfering--therapeutic use.
- Medical Subjects:
- Gene Transfer Techniques.
- Genetic Therapy--methods.
- Genetic Vectors--therapeutic use.
- Huntington Disease--therapy.
- MicroRNAs--therapeutic use.
- Nervous System Diseases--therapy.
- RNA Interference.
- RNA, Small Interfering--therapeutic use.
- Physical Description:
- 1 videorecording (48 min., 29 sec.) : sound, color.
- Place of Publication:
- London : Henry Stewart Talks, 2014.
- System Details:
- video file
- Contents:
- Contents: Repeat expansion diseases
- Polyglutamine (polyQ) repeat diseases
- Huntington's disease
- Vectors for delivering genetic material to brain
- AAVs for delivering RNAi for reducing gene expression
- Artificial miRNAs
- Testing miHD for efficacy
- Off-target silencing
- MRI-guided delivery of AAV into primates
- HTT suppression
- Other gain-of function diseases
- Targeted infusion for broad coverage
- Silencing ataxin-1
- Nonallele specific silencing: experimental design
- Expression and activity of miSCA1.
- Notes:
- Animated audio-visual presentation with synchronized narration.
- Title from title frames.
- Publisher Number:
- 3789 Henry Stewart Talks
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