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Receptor identification for alarmins and DAMPs / Joost J. Oppenheim.

Henry Stewart Biomedical & Life Sciences Collection Available online

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Format:
Video
Author/Creator:
Oppenheim, Joost J., author.
Language:
English
Subjects (All):
Cell receptors.
Physical Description:
1 video recording (49 min., 26 sec.) : sound, color
Place of Publication:
London : Henry Stewart Talks Ltd., 2011.
System Details:
video file
Contents:
Introduction
hBD2's chemotactic effect and receptor
DCs' activating effect of beta-defensin-2
Alarmins recruit and activate APC
Definition of DAMPs
Antimicrobial proteins act as alarmins
Mechanism of action of alarmins: granulysin
Granulysin activates DCs by TLR4
Anti-granulysin blocks the DC-activating effect
NK92 supernatant activates DCs by TLR4
No endotoxin contamination in granulysin effect
Alarming effects of granulysin
Why study HMGN1?
HMGN1 induction of DC recruitment.
Notes:
Description based on: online resource; title from information screen (HSTalks, viewed April 17, 2024).
Retrieved April 17, 2024, from https://hstalks.com/bs/2156/.

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