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Receptors and channels in pain / Tony Dickenson.

Henry Stewart Biomedical & Life Sciences Collection Available online

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Format:
Video
Author/Creator:
Dickenson, A. H., Speaker.
Series:
Henry Stewart talks. Biomedical & life sciences collection. Synapses, neurotransmitters and receptor channels.
Synapses, neurotransmitters and receptor channels, 2056-452X
Language:
English
Subjects (All):
Analgesia.
Central nervous system--Physiology.
Central nervous system.
Ion channels.
Nociceptors.
Pain.
Synapses--Physiology.
Synapses.
Analgesics--pharmacology.
Analgesics--therapeutic use.
Central Nervous System--physiology.
Ion Channels--physiology.
Nociceptors--drug effects.
Nociceptors--physiopathlogy.
Pain--drug therapy.
Pain--physiopathology.
Receptors, Neurotransmitter.
Synapses--physiology.
Medical Subjects:
Analgesics--pharmacology.
Analgesics--therapeutic use.
Central Nervous System--physiology.
Ion Channels--physiology.
Nociceptors--drug effects.
Nociceptors--physiopathlogy.
Pain--drug therapy.
Pain--physiopathology.
Receptors, Neurotransmitter.
Synapses--physiology.
Physical Description:
1 videorecording (44 min., 45 sec.)
Place of Publication:
London : Henry Stewart Talks, 2014.
System Details:
video file
Contents:
Contents: CNS pain circuits
Receptors, ligands , mediators & ion channels involved in pain signaling
Key types of pain
Inflammation (ongoing activation of pain sensors)
Nerve growth factor and bone innervation
Tanezumab: humanized monoclonal antibody
Symptoms of neuropathic pain
Sodium channel changes, redistribution, activation
Channelopathic pain syndromes
Pregabalin and gabapentin
Ca channels
Peripheral activity causes central hyperexcitability
Post-synaptic neuron activation
Spinal mechanisms
NMDA receptors
Central sensitization
Noradrenaline and 5HT
Pain sensitivity: pathway alterations
Reduced NA\increased 5HT function: effects
Diffuse Noxious Inhibitory Controls (DNIC)
Morphine and codeine
Opioid mechanisms
Pain signaling, multi-level changes & drug targets
Similar symptoms\signs: many mechanisms.
Notes:
Description based on: online resource; title from PDF information screen (Henry Stewart Talks Business & Management Collection, viewed April 5, 2024).
Animated audio-visual presentation with synchronized narration.
Title from title frames.
Publisher Number:
3615 Henry Stewart Talks

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