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Intestinal stem cell-mediated repair in Drosophila : Part 2 of 2 / Tony Ip.
Henry Stewart Biomedical & Life Sciences Collection Available online
Henry Stewart Biomedical & Life Sciences Collection- Format:
- Video
- Author/Creator:
- Ip, Tony, (University of Massachusetts Medical School, USA), Speaker.
- Series:
- Henry Stewart talks. Biomedical & life sciences collection. Legacy of Drosophila genetics : from 'defining the gene' to 'analyzing genome function'.
- The legacy of Drosophila genetics : from 'defining the gene' to 'analyzing genome function', 2056-452X
- Language:
- English
- Subjects (All):
- Drosophila--Cytology.
- Stem cells.
- Drosophila melanogaster--cytology.
- Drosophila melanogaster.
- Intestines--cytology.
- Intestines--pathology.
- Stem Cells--cytology.
- Stem Cells--metabolism.
- Medical Subjects:
- Drosophila melanogaster--cytology.
- Drosophila melanogaster.
- Intestines--cytology.
- Intestines--pathology.
- Stem Cells--cytology.
- Stem Cells--metabolism.
- Physical Description:
- 1 videorecording (30 mins., 24 sec.) : sound, color
- Other Title:
- Intestinal stem cell-mediated repair in Drosophila, part 2
- Place of Publication:
- London : Henry Stewart Talks, 2014.
- System Details:
- video file
- Contents:
- Contents: The adult Drosophila midgut contains tissue specific intestinal stem cells (ISCs)
- ISCs are the only dividing cells in the midgut and are responsible for maintaining midgut homeostasis and regeneration
- The ISC division gives rise to a renewed stem cell and an enteroblast, which can differentiate into secretory enteroendocrine cells or absorptive enterocytes
- Intrinsic factors such as Tuberous Sclerosis Complex and Myc coordinate the growth and division of ISCs
- Extrinsic factors such as Epidermal Growth Factor from surrounding cells and the interaction with basement membrane also regulate the rate of ISC division
- Insulin secreted from CNS function as a long-range growth factor to control ISC activity and therefore intestinal tissue homeostasis.
- Notes:
- Description based on: online resource; title from PDF information screen (Henry Stewart Talks Biomedical and Life Sciences Collection, viewed April 5, 2024).
- Animated audio-visual presentation with synchronized narration.
- Title from title frames.
- Publisher Number:
- 3689 Henry Stewart Talks
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