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Ciliopathies and oligogenic phenomena / Nicholas Katsanis.

Henry Stewart Biomedical & Life Sciences Collection Available online

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Format:
Video
Author/Creator:
Katsanis, Nicholas, (Duke University, USA), Speaker.
Series:
Henry Stewart talks. Biomedical & life sciences collection. Molecular genetics of human disease.
Molecular genetics of human disease, 2056-452X
Language:
English
Subjects (All):
Cilia and ciliary motion.
Human molecular genetics.
Medical genetics.
Systems biology.
Alleles.
Cilia--genetics.
Cilia--pathology.
Genetics, Medical.
Genome, Human.
Mutation--genetics.
Phenotype.
Systems Biology.
Medical Subjects:
Alleles.
Cilia--genetics.
Cilia--pathology.
Genetics, Medical.
Genome, Human.
Mutation--genetics.
Phenotype.
Systems Biology.
Physical Description:
1 videorecording (54 min., 55 sec.) : sound, color.
Place of Publication:
London : Henry Stewart Talks, 2015.
System Details:
video file
Contents:
Contents: Ciliopathies: multisystemic disorders caused by structural and/or functional defects of the primary cilium
Mutations in almost 100 genes discovered to date, no clear pattern between specific genes and specific phenotypes
Functional interpretation of variants critical for understanding the contribution of alleles to disease severity and pleiotropy
A systems-based consideration for the total amount of pathogenic variation in the ciliary proteome begins to predict clinical substructure.
Notes:
Description based on publisher supplied metadata and other sources.
Animated audio-visual presentation with synchronized narration.
Title from title frames.
Publisher Number:
3712 Henry Stewart Talks

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