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Mitochondria and calcium signaling in cell life and cell death / Michael R. Duchen.
- Format:
- Video
- Author/Creator:
- Duchen, Michael R., Speaker.
- Series:
- Henry Stewart talks. Biomedical & life sciences collection. Mitochondria in health and disease.
- Mitochondria in health and disease, 2056-452X
- Language:
- English
- Subjects (All):
- Calcium--Metabolism.
- Calcium.
- Calcium--Physiological effect.
- Cell death.
- Cellular signal transduction.
- Mitochondria.
- Calcium Metabolism Disorders.
- Calcium Signaling.
- Cell Death.
- Cytosol--metabolism.
- Mitochondria--metabolism.
- Mitochondria--physiology.
- Mitochondrial Membrane Transport Proteins.
- Mitochondrial Permeability Transition Pore.
- Neuromuscular Diseases.
- Oxidative Phosphorylation.
- Permeability.
- Medical Subjects:
- Calcium Metabolism Disorders.
- Calcium Signaling.
- Cell Death.
- Cytosol--metabolism.
- Mitochondria--metabolism.
- Mitochondria--physiology.
- Mitochondrial Membrane Transport Proteins.
- Mitochondrial Permeability Transition Pore.
- Neuromuscular Diseases.
- Oxidative Phosphorylation.
- Permeability.
- Physical Description:
- 1 online resource (1 streaming video file (38 min.)) : color, sound
- Place of Publication:
- London : Henry Stewart Talks, 2018.
- System Details:
- video file
- Contents:
- Contents: Calcium signalling, ubiquitous and associated with increased energy demand
- Mitochondria machinery to for taking up calcium from the cytosol
- The transfer of calcium from cytosol to mitochondria (stimulation of oxidative phosphorylation & matching energy supply with demand)
- Mutations in proteins that regulate mitochondrial calcium uptake (causation of a neuromuscular disease, possibly by mitochondrial calcium overload)
- Acute severe calcium overload causes cell death during reperfusion of ischaemic tissues
- The permeability transition pore, a potential therapeutic target.
- Notes:
- Description based on publisher supplied metadata and other sources.
- Animated audio-visual presentation with synchronized narration.
- Title from title frames.
- Publisher Number:
- 4513 Henry Stewart Talks
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