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The role of Neuropilin-1 as a SARS-CoV-2-specific endocytosis potentiator / an interview with Yohei Yamauchi.

Henry Stewart Biomedical & Life Sciences Collection Available online

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Format:
Sound recording
Author/Creator:
Yamauchi, Yohei, (The University of Bristol, UK), Speaker.
Series:
Henry Stewart talks. Biomedical & life sciences collection. Interviews on Covid-19.
Interviews on Covid-19, 2056-452X
Language:
English
Subjects (All):
Cell receptors.
Coronaviruses.
COVID-19 (Disease)--Research.
COVID-19 (Disease).
Drug development.
Host-virus relationships.
Angiotensin-Converting Enzyme 2.
Antiviral Agents.
Betacoronavirus--physiology.
Coronavirus Infections.
COVID-19--virology.
Endocytosis.
Epithelium.
Lung.
Neuropilin-1.
SARS-CoV-2.
Spike Glycoprotein, Coronavirus--metabolism.
Virus Internalization.
Medical Subjects:
Angiotensin-Converting Enzyme 2.
Antiviral Agents.
Betacoronavirus--physiology.
Coronavirus Infections.
COVID-19--virology.
Endocytosis.
Epithelium.
Lung.
Neuropilin-1.
SARS-CoV-2.
Spike Glycoprotein, Coronavirus--metabolism.
Virus Internalization.
Physical Description:
1 online resource (1 streaming audio file (11 min., 00 sec.))
Place of Publication:
London : Henry Stewart Talks, 2021.
System Details:
video file
Contents:
Contents: Differences in the structure and biological properties of SARS-CoV-2 Spike proteins compared to those of other coronaviruses (including SARS)
The distinct profile of the distribution of SARS-CoV-2-infected cells, particularly in lung and epithelial tissue, compared to other coronaviruses
SARS-CoV-2's Spike protein sequence grants it the unique ability to interact with Neuropilin-1, in addition to ACE2
Role of Neuropilin-1, a cell-surface co-receptor, in facilitating mechanisms of SARS-CoV-2 entry into cells
Current understanding of the influence of Neuropilin-1 on the development of COVID-19 and on disease progression
The potential of developing SARS-CoV-2-specific antiviral drugs targeting Neuropilin-1.
Notes:
Description based on: online resource; title from information screen (HSTalks, viewed April 14, 2024).
Audio interview.
Title from title frames.
Publisher Number:
8214 Henry Stewart Talks

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