Historical introduction to human diversity II / D. M. Swallow.

Format:

Video

Author/Creator:

Swallow, D. M., author.

Language:

English

Subjects (All):

Human evolution.

Human evolution--Effect of technological innovations on.

Physical Description:

1 videorecording (28 min., 24 sec.) : sound, color

Place of Publication:

London : Henry Stewart Talks, 2009.

System Details:

video file

Contents:

Introduction

Electrophoresis: a powerful technique in genetics

Electrophoretic mobility

Mobility of two different amino-acids

Harry Harris (1919-1994)

Specific detection methods

Mutation in phosphoglucomutase 1 (PGM1)

Detecting size differences by electrophoresis

Subtle changes - isoelectric focussing

Protein polymorphism

DNA polymorphism and electrophoresis

Detection of size and conformational differences

Detection of different number of tandem repeats

Genotype and phenotype

Crosses in the ABO blood group system

Difficulties in interpreting the correct genotype

Epistasis

Multiple molecular forms or isozymes/forms

Many proteins are encoded by multiple genes

Subunits of phosphorylase kinase

Multimeric proteins

Subunits of lactate dehydrogenase

Electrophoresis of samples from three people

Distinguishing multiple genes from multiple alleles

Analysis of enzyme polymorphism and isozyme

Human genome sequence HapMap

Functional implications of genetic variation.

Notes:

Description based on publisher supplied metadata and other sources.

Retrieved April 19, 2024, from https://hstalks.com/bs/1562/.