Thalamo-cortical pain mechanisms / Fred A. Lenz, F. H. Baker.

Format:

Video

Author/Creator:

Lenz, Fred A., author.

Baker, F. H., author.

Language:

English

Subjects (All):

Cerebral cortex.

Thalamus.

Physical Description:

1 videorecording (40 mins., 41 sec.) : sound, colour

Place of Publication:

London, England : Henry Stewart Talks Ltd, 2009.

System Details:

video file

Contents:

Introduction

Locations in brain activated by pain stimuli

Spinal thalamic tract (1)

Spinal thalamic tract (2)

Spinal thalamic tract cells respond to pain

Different cells in the spinal thalamic tract

Recording from cells in the superficial dorsal horn

inhibition by warming

Cold receptive cluster and nociceptor specific cells

Lamina I vs. deep laminar neurons of origin

Different cells respond to different pain stimuli (1)

Different cells respond to different pain stimuli (2)

Evidence against a pain specific thalamic nucleus

Calbinden staining and STT staining do not overlap

Selective injection- VP nucleus

Activity in the thalamic relay to cortex

Recordings in a human thalamus

Anatomy of the somatic sensory thalamus

A cell in VC responding to painful stimuli

A cell in VC responding to brush

Firing is not always at a steady rate

Thalamocortical non-linearities

Intense bursts of firing occur post inhibition

Thalamocortical circuity

Pain evoked by electric stimulation

Stimulation of many cells in one patient

Different stimulation sites overlap

Effect of different pattern on the evoked sensation

Visual analog scale of pain intensity

Transmission of visceral sinals in the spinal cord

Neuron response to different organ distension (1)

Somatovisceral convergence in the lateral thalamus

Sites of cardiac pain evoked by stimulation

Which words describe the sensation you feel?

Effects of thalamic lesions

Effect of local anasthetic injection

Studies of the cortex

WDR cell responses

Distribution of LEPs

Intensity of LEP should vary with intensity of pain

LEPs, v-SEPs, e-SEPs located on similar areas

Cells responding to noxious stimuli

Nociceptive input to the cortical projection zones

BESA estimate of dipole locations

Lesions and parasylvian pain related activity

Lesion evidence: the insula

Insular lesions associated with pain tolerance

Responses to attention

ACC lesions - associated with higher pain intensity

Functional connectivity and networks

SI vs. parasylvian - attention condition

Prestimulus PLV- attention and distraction

Post prestimulus PLV- attention and distraction

Task-specific functional connectivity.

Notes:

Description based on: online resource; title from PDF information screen (Henry Stewart Talks Biomedical and Life Sciences Collection, viewed April 5, 2024).

Retrieved April 10, 2024, from https://hstalks.com/bs/1130/.