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Macrophages, a cellular toolbox used by tumors to promote progression and metastasis / Jeffrey W. Pollard.

Henry Stewart Biomedical & Life Sciences Collection Available online

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Format:
Video
Author/Creator:
Pollard, Jeffrey W., author.
Language:
English
Subjects (All):
Natural immunity.
Physical Description:
1 online resource (1 streaming video file (48 min., 32 sec.)) : sound, color
Place of Publication:
London, England : Henry Stewart Talks, 2009.
System Details:
video file
Contents:
Introduction
Intravital imaging of macrophages
Macrophages functions
TAMs subvert normal macrophage functions
Tumor-stroma interactions
TAMs density and prognosis
CSF-1 and macrophage chemokines
CSF-1 promotes tumor progression to metastasis?
A robust staging system for PyMT tumors
Delayed tumor progression without macrophages
Pulmonary metastasis inhibition
CSF-1 and tumor regulation
CSF-1 expression in mammary gland
Macrophages staining in the -/- (CSF-1 Tg+) mice
Tumor progression at 18 weeks of age
TAMs density in tumor
Macrophages promote invasive microenvironment
Tumor cells migration and macrophages
Micro needle invasion assay
Needle collection and CSF-1 and EGF signalling
Cell specific gene expression profiles
Needle collection of cells requires macrophages
Tumor cell macrophage interaction
Macrophages and tumor cells
Paracrine loop-relayed chemotaxis
The six traits
Vessel network formation and tumor progression
Malignancy and the angiogenic switch
Stage of macrophages recruitment
Angiogenesis mechanism
Vessel network formation in WT/ CSF1 null mice
Macrophage depletion reduces vascularization
Macrophage depletion and vessel area and density
IHC of VEGF in PyMT tumor
VEGF expression vector using the 2A system
VEGF effect
VEGF over-expression
Introducing macrophages in an earlier stage
CSF-1 effect
CSF-1 over expression
CSF-1 transgenic expression
Tumor movement and macrophages
Where do the macrophages localize?
Tumor cell motility
Intravasation
The invasive microenvironment
Paracrine interactions
Acknowledgements.
Notes:
Description based on: online resource; title from PDF information screen (Henry Stewart Talks Biomedical and Life Sciences Collection, viewed April 12 2024).
Retrieved April 12, 2024, from https://hstalks.com/bs/1319/.

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