1 option
Immunodeficiencies and genetic mutations affecting NK cells in humans / Jordan S. Orange.
- Format:
- Video
- Author/Creator:
- Orange, Jordan S., author.
- Language:
- English
- Subjects (All):
- Cell-mediated cytotoxicity.
- Physical Description:
- 1 online resource (1 streaming video file (53 min., 22 sec.)) : sound, color
- Place of Publication:
- London, England : Henry Stewart Talks, 2009.
- System Details:
- video file
- Contents:
- Introduction
- NK cell functions
- NK cell inhibition
- NK cell activation (missing self)
- NK cells in defense
- Measuring cytotoxicity
- The NK cell lytic immunological synapse
- NK cell synapse (3-D reconstruction)
- NK cell synapse (electron micrograph)
- NK cells and human single gene deficiencies
- Wiskott-Aldrich syndrome and NK cells
- NK cell deficiency in Wiskott-Aldrich syndrome
- WASp function
- WASp and F-actin accumulation
- WASP deficiency affects F-actin accumulation
- WASp is essential for synapse events
- Lytic granule traffic requires microtubules
- The sequence of events leading to the synapse
- Stages of lytic immunological synapse formation
- Steps in lytic immunological synapse formation
- A video of immunological synapse formation
- Case presentation I - history
- Case presentation II- laboratory studies
- Case presentation III - clinical course
- Case presentation IV - NK cell function
- HLH diagnostic guidelines
- Management of HLH
- Case presentation V - diagnosis of FEL3
- Hematophagocytic lymphohistiocytosis
- Model for HLH
- Molecular defects leading to HLH
- Steps in immune-mediated cytolysis
- Single gene diseases and NK cell defects (1)
- Single gene diseases and NK cell defects (2)
- NK cell population: age-specific normal varies
- Isolated deficiencies of NK cells in humans
- ANKD
- CNKD
- FNKD
- What suggests NKD
- Practical approach to NKD
- Comprehensive approach to NKD
- Management of NKD
- Conclusions.
- Notes:
- Description based on: online resource; title from PDF information screen (Henry Stewart Talks Biomedical and Life Sciences Collection, viewed April 12 2024).
- Retrieved April 12, 2024, from https://hstalks.com/bs/1458/.
The Penn Libraries is committed to describing library materials using current, accurate, and responsible language. If you discover outdated or inaccurate language, please fill out this feedback form to report it and suggest alternative language.