START control in yeast / Curt Wittenberg.

Format:

Video

Author/Creator:

Wittenberg, Curt, author.

Language:

English

Subjects (All):

Cell division.

Cell cycle.

Physical Description:

1 videorecording (36 min., 30 sec.)

Place of Publication:

London : Henry Stewart Talks Ltd, 2009.

System Details:

video file

Contents:

Introduction

Control of cell proliferation

The budding yeast: Saccharomyces cerevisiae

Why yeast?

The budding yeast life cycle

Placement of START in the cell cycle

Observing START

The concept of "START" - The G1 checkpoint

Genetic characterization of START

Interdependency of Cdk1 with START regulators

Cyclin-dependent protein kinase (CDK)

The cyclin/CDK cycle

G1 cyclin/CDK is essential for START

The role of CDK in START

Periodic expression of Far1 and cyclins

Cell cycle regulators accumulation in G1

The molecular correlate of START

G1-specific transcription

Phosphorylation of Whi5 by Cln3

Repression of MBF and SBF as cells exit G1

Conservation of G1-specific transcription regulators

G1-specific gene expression and human cancer

The molecular determinant of START - summary

Physiological regulators of START

Mating generates diploid cells from haploid cells

Cells of opposite mating types can conjugate

Responses elicit by mating pheromone cascade

Mating pheromone signaling pathway

Far1 activation by mating pheromones

Regulation of START by other stimuli

Control of START by cell size

The molecular basis for the Sizer and Timer

Possible signals for achieving minimum cell size

Summary

Related reading.

Notes:

Description based on: online resource; title from PDF information screen (Henry Stewart Talks Business & Management Collection, viewed April 12, 2024).

Retrieved April 12, 2024, from https://hstalks.com/bs/1253/.