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Regulation of type 2 immunity by basophils / David Voehringer.
- Format:
- Video
- Author/Creator:
- Voehringer, David, author.
- Language:
- English
- Subjects (All):
- Basophils.
- Physical Description:
- 1 streaming video file (32 min.) : color, sound
- Place of Publication:
- London : Henry Stewart Talks Ltd, 2012.
- System Details:
- video file
- Contents:
- Introduction
- Outline of the presentation
- Type 1 vs. Type 2 immunity
- Type 2 immunity - a double-edged sword
- Development of a type 2 immune response
- Discovery of innate type 2 effector cells
- Basophils, mast cells and eosinophils
- Developmental relationship
- Detection of basophils by CD49b/IgE staining
- Nippostrongylus brasiliensis infection
- N. brasiliensis infected lung
- N. brasiliensis infected small intestine
- Analysis of basophil turnover in vivo
- Activating receptors on basophils
- Activation of basophils by IgE
- Cytokine instruction of basophils
- Basophil effector functions
- Generation & analysis of basophil-deficient mice
- Mast cell protease 8 is expressed in basophils
- Deletion of basophils in Mcpt8Cre mice
- Mast cells are not deleted in Mcpt8Cre mice
- Effector function of basophils
- Are basophils required for Th2 polarization?
- DCs or basophils for Th2 polarization? (1)
- Generation of DC-deficient mice
- DCs or basophils for Th2 polarization? (2)
- DCs are required for Th2 polarization
- Role of innate IL-4 for Th2 polarization
- Innate IL-4/IL-13 regulates Th2 accumulation
- Basophils in anaphylactic responses
- IgG1-mediated systemic anaphylaxis
- Basophils aren't required for anaphylaxis
- Basophils in chronic allergic inflammation of skin
- Basophils are required for allergic inflammation
- Basophil response against helminths and ticks
- Primary response to N. brasiliensis
- Expulsion kinetics of N. brasiliensis
- Protective immunity against N. brasiliensis
- Basophils during secondary infection
- Protective immunity against ticks
- Summary
- Acknowledgements.
- Notes:
- Description based on publisher supplied metadata and other sources.
- Retrieved April 13, 2024, from https://hstalks.com/bs/2288/.
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