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Innate immunity in the intestine in health and disease / Kevin Maloy.
- Format:
- Video
- Author/Creator:
- Maloy, Kevin, author.
- Language:
- English
- Subjects (All):
- Immunity, Innate.
- Natural immunity.
- Physical Description:
- 1 streaming video file (42 min.) : sound, color
- Place of Publication:
- London, England : Henry Stewart Talks Ltd, 2013.
- System Details:
- video file
- Contents:
- Introduction
- Importance of innate immunity in the gut
- Mucosal tissues of the human body
- Intestinal pathogens and human disease
- Mucosal immune system: distinctive features
- Gut-associated lymphoid tissue (GALT)
- Structure of the GALT: small intestine
- Structure of the GALT: large intestine
- Mucus forms a key protective barrier in the gut
- Mucus secretion increases during infection
- Antimicrobial proteins protect the epithelium
- Epithelial cell transcytosis of secretory IgA
- Functions of secretory IgA
- Uptake and transport of antigen by M cells
- Microbial sensing regulates intestinal homeostasis
- Sensing of microbes occurs through PRR
- Innate immune signaling (1)
- Innate immune signaling (2)
- PRR signals in IEC
- MyD88 signals in IEC
- Control of inflammatory responses in the intestine
- Intestinal macrophages are anti-inflammatory
- Intestinal DC 'conditioning'
- Inflammatory bowel disease (IBD)
- Genome-wide association studies
- The enigma of NOD2 and Crohn's disease
- NOD2 signaling in response to bacterial MDP
- NOD2 signaling in IEC
- NOD2 signaling regulates myeloid cell function
- Autophagy also regulates IEC and myeloid cells
- Innate immune activation in IBD pathogenesis
- Innate intestinal inflammation, MyD88 dependent
- MyD88 activation drives intestinal inflammation
- Haematopoeitic MyD88 signals
- Immune dysregulation in chronic inflammation
- Innate lymphoid cells (ILC) drive innate IBD
- ILC provide early innate immune protection
- Additional distinct functional subsets of ILC
- Leukocyte populations and intestinal homeostasis
- Summary
- Acknowledgements.
- Notes:
- Description based on publisher supplied metadata and other sources.
- Retrieved April 15, 2024, from https://hstalks.com/bs/2486/.
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