What can we learn from conformational profiling of GPCRs? / Terry Hébert.

Format:

Video

Author/Creator:

Hébert, Terry, (McGill University, Canada), Speaker.

Series:

Henry Stewart talks. Biomedical & life sciences collection. G Protein-Coupled Receptors (GPCRs) signaling in health and disease.

G Protein-Coupled Receptors (GPCRs) signaling in health and disease, 2056-452X

Language:

English

Subjects (All):

Cellular signal transduction.

Drug development--Methodology.

Drug development.

G proteins--Receptors.

G proteins.

Proteins--Conformation.

Proteins.

Chemistry, Pharmaceutical--methods.

Chemistry, Pharmaceutical--trends.

Drug Discovery--methods.

Protein Conformation.

Receptors, G-Protein-Coupled--chemistry.

Receptors, G-Protein-Coupled--metabolism.

Signal Transduction--drug effects.

Signal Transduction--physiology.

Technology, Pharmaceutical--methods.

Medical Subjects:

Chemistry, Pharmaceutical--methods.

Chemistry, Pharmaceutical--trends.

Drug Discovery--methods.

Protein Conformation.

Receptors, G-Protein-Coupled--chemistry.

Receptors, G-Protein-Coupled--metabolism.

Signal Transduction--drug effects.

Signal Transduction--physiology.

Technology, Pharmaceutical--methods.

Physical Description:

1 videorecording (01 hr., 07 min., 47 sec.) : sound, color

Place of Publication:

London : Henry Stewart Talks, 2020.

System Details:

video file

Contents:

Contents: Biased signaling will have an impact in clinical medicine

Pharma is moving into using signaling signatures to capture information during drug discovery process

The information of signaling signatures can never be "complete"

Conformational profiling may offer a huge time savings rather than extending signaling signatures

Conformational profiling needs to be done in relevant cell, tissue and animal models.

Notes:

Description based on publisher supplied metadata and other sources.

Animated audio-visual presentation with synchronized narration.

Title from title frames.

Publisher Number:

5105 Henry Stewart Talks