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An introduction to statistical genetic data analysis / Melinda C. Mills, Nicola Barban, and Felix C. Tropf.
- Format:
- Book
- Author/Creator:
- Mills, Melinda, author.
- Barban, Nicola, author.
- Tropf, Felix C., 1984- author.
- Language:
- English
- Subjects (All):
- Genetics--Statistical methods.
- Genetics.
- Genomics--Statistical methods.
- Genomics.
- Genomics--Data processing.
- Data Interpretation, Statistical.
- Genome-Wide Association Study.
- Gene-Environment Interaction.
- Models, Theoretical.
- Medical Subjects:
- Data Interpretation, Statistical.
- Genomics.
- Genome-Wide Association Study.
- Gene-Environment Interaction.
- Models, Theoretical.
- Physical Description:
- 1 online resource (xvi, 415 pages) : illustrations, maps.
- Place of Publication:
- Cambridge, Massachusetts : The MIT Press, [2020]
- Contents:
- Introduction : Fundamental Concepts and the Human Genome
- A Statistical Primer for Genetic Data Analysis
- A Primer in Human Evolution
- Genome-Wide Association Studies (GWAS)
- Introduction to Polygenic Scores and Genetic Architecture
- Gene-Environment Interplay
- Genetic data and analytical challenges
- Working with genetic data Part I : Data management, descriptive statistics and quality control
- Working with genetic data Part II : Association analysis, population stratification, and genetic relatedness
- An applied guide to creating and validating polygenic scores
- Polygenic Score and Gene-Environment Interaction (GxE) Applications
- Applying genome-wide association results
- Mendelian Randomization and instrumental variables
- Ethical Issues in Genomics Research
- Conclusions and Future Directions.
- Notes:
- Includes bibliographical references and index.
- Electronic reproduction. Ann Arbor, MI Available via World Wide Web.
- Description based on print version record.
- ISBN:
- 9780262357449 (electronic bk.)
- 0262357445 (electronic bk.)
- Publisher Number:
- 99995717199
- Access Restriction:
- Restricted for use by site license.
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