Genes, Environments and Interactions : Evolutionary and Quantitative Genetics Brought Up-to-date / by José M Álvarez-Castro.

Format:

Book

Author/Creator:

Álvarez-Castro, Jose M., author.

Language:

English

Subjects (All):

Evolutionary genetics.

Biomathematics.

Evolution (Biology).

Ecological genetics.

Population genetics.

Evolutionary Genetics.

Mathematical and Computational Biology.

Evolutionary Biology.

Ecological Genetics.

Population Genetics.

Evolutionary Theory.

Local Subjects:

Evolutionary Genetics.

Mathematical and Computational Biology.

Evolutionary Biology.

Ecological Genetics.

Population Genetics.

Evolutionary Theory.

Physical Description:

1 online resource (236 pages)

Edition:

1st ed. 2023.

Place of Publication:

Cham : Springer International Publishing : Imprint: Springer, 2023.

Summary:

Genetic effects are the core concepts from which quantitative genetics and the evolutionary synthesis emerged. The groundbreaking theory of genetic effects was first proposed over a century ago. This book revises that theory, both conceptually and mathematically, and brings it up-to-date. The theory here compiled is supplemented with non-previously-published developments covering the broadest spectrum of simultaneously multiallelic and multilocus architectures with autosomal and sex-linked loci Arbitrary interactions (dominance, gene-gene, gene-environment, gene-sex, and parent-of-origin interactions) are accounted for Both effects of allele substitutions from the reference of individual genotypes and in the context of populations are worked out Populations are considered regardless of any departures from equilibrium frequencies (including both departures from Hardy-Weinberg, departures from linkage equilibrium, and non-random associations between/among genes and environments) All developments are derived under the same mathematical framework, so that transformations of genetic effects between different contexts are easily allowed In brief, this book enables novel applications to current empirical paradigms (like gene-mapping and genomic prediction) while adhering to the classical conceptualization of genetic effects and variance decomposition that let quantitative genetics and the evolutionary synthesis flourish. All relevant concepts are carefully clarified and discussed from a historical perspective. The theoretical developments presented in the book are illustrated by built-in cases and applications with real data. Reassuringly, the adequacy of the theory here presented is corroborated based on the fundamentals of model development.

Contents:

Chapter 1: Discovering The Genotype

Chapter 2: The Primeval Theory Of Ge-Netic Effects

Chapter 3: Genetic Effects Over One Century

Chapter 4: Hgenetic Architectures At The Individual Level

Chapter 5: Genetic Effects In Popula-Tions Under Linkage Equilibrium

Chapter 6: A General Theory Of Genetic Effects

Chapter 7: Variance Decomposition, Gene Mapping And Average Excesses—Orthogonality In The Spotlight

Chapter 8: Applied Cases Of Advanced Genetic Modelling

Chapter 9: The Comes And Goes Of The Black Box Perspective In Quantitative Genetics

Chapter 10: Addendum: An Acid Test For Noia.

Notes:

Includes bibliographical references and index.

Other Format:

Print version: Álvarez-Castro, José M. Genes, Environments and Interactions

ISBN:

9783031411595

3031411595