Optical Polarimetric Modalities for Biomedical Research / edited by Nirmal Mazumder, Yury V. Kistenev, Ekaterina Borisova, Shama Prasada K.

Format:

Book

Contributor:

Mazumder, Nirmal, editor.

Series:

Biological and Medical Physics, Biomedical Engineering, 2197-5647

Language:

English

Subjects (All):

Optics.

Biology--Technique.

Biology.

Biophysics.

Materials--Analysis.

Materials.

Materials--Microscopy.

Applied Optics.

Biophysical Methods.

Materials Characterization Technique.

Microscopy.

Local Subjects:

Applied Optics.

Biophysical Methods.

Materials Characterization Technique.

Microscopy.

Physical Description:

1 online resource (455 pages)

Edition:

1st ed. 2023.

Place of Publication:

Cham : Springer International Publishing : Imprint: Springer, 2023.

Summary:

This book focuses on polarization microscopy, a powerful optical tool used to study anisotropic properties in biomolecules, and its enormous potential to improve diagnostic tools for various biomedical research. The interaction of polarized light with normal and abnormal regions of tissue reveals structural information associated with its pathological condition. Diagnosis using conventional microscopy can be time-consuming, as pathologists require an hour to freeze and stain tissue slices from suspected patients. In comparison, polarization microscopy more quickly distinguishes abnormal tissue and provides better microstructural information of samples, even in the absence of staining. This book provides a basic understanding of the properties of polarized light, a description of the polarization microscope, and a mathematical formalism of Mueller matrix polarimetry. The authors discuss various advanced linear and nonlinear optical techniques such as optical coherence tomography (OCT), reflectance and transmission spectroscopy, fluorescence, multiphoton excitation, second harmonic generation, Raman microscopy, and more. They explore the exciting potential of integrating polarimetry with these techniques for possible applications in different areas of biomedical research, as well as the associated challenges. Including the most recent developments on the topic, this book serves as a modern guide to polarization microscopy and advancements in its use in biomedical research.

Contents:

PartI. Stokes Mueller based polarimetry

Chapter1. Polarization imaging of optical anisotropy in soft tissues

Chapter2. Polarization techniques in biological microscopy

Chapter3. Stokes Mueller Matrix Polarimetry: Effective Parameters of Anisotropic Turbid Media - Theory and Application

Chapter4. Mueller matrix imaging

Chapter5. Biological imaging through optical Mueller-matrix scanning microscopy

Chapter6. Mueller polarimetry for biomedical applications

Chapter7. Scattering phase functions and polarimetric responses of selected bioparticles

PartII. Nonlinear polarization microscopy

Chapter8. Polarization resolved nonlinear optical microscopy

Chapter9. Polarization-resolved SHG microscopy for biomedical applications

Chapter10. Polarization-resolved second harmonic generation for tissue imaging

PartIII. Applications of polarization techniques

Chapter11. An Introduction to Fundamentals of Cancer Biology

Chapter12. Polarization enabled optical spectroscopy and microscopy techniques for cancer diagnosis

Chapter13. Polarization Microscopy in Biomedical Applications

Chapter14. Machine learning in tissue polarimetry. .

Notes:

Includes bibliographical references and index.

Other Format:

Print version: Mazumder, Nirmal Optical Polarimetric Modalities for Biomedical Research

ISBN:

3-031-31852-8