Spatially fractionated, microbeam and FLASH radiation therapy : a physics and multi-disciplinary approach / edited by Hualin Zhang, Nina A. Mayr.

Format:

Book

Contributor:

Zhang, Hualin (Medical physicist), editor.

Mayr, Nina A., editor.

Institute of Physics (Great Britain), publisher.

Series:

IOP (Series). Release 23.

IPEM-IOP series in physics and engineering in medicine and biology

IOP ebooks. 2023 collection.

[IOP release $release]

IOP ebooks. [2023 collection]

Language:

English

Subjects (All):

Cancer--Radiotherapy.

Cancer.

Medical physics.

Neoplasms--radiotherapy.

Radiation Oncology--methods.

Medical Subjects:

Neoplasms--radiotherapy.

Radiation Oncology--methods.

Physical Description:

1 online resource (various pagings) : illustrations (some color).

Place of Publication:

Bristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK) : IOP Publishing, [2023]

System Details:

Mode of access: World Wide Web.

System requirements: Adobe Acrobat Reader, EPUB reader, or Kindle reader.

Biography/History:

Hualin Zhang, PhD is an Associate Professor in the Department of Radiation Oncology at the University of Southern California. Prior to that he held the position of the chief physicist of brachytherapy in the Department of Radiation Oncology at Northwestern University Feinberg School of Medicine. He serves as chair of the Radiosurgery Society GRID/Lattice, Microbeam and FLASH Radiation Therapy Physics Working Group; and as the chair of the AAPM Intraoperative Mesh Brachytherapy Working Group. He has published over 50 peer reviewed journal articles. He is recipient of the Outstanding Teacher Award there in 2018. Nina A Mayr, MD is Professor and Senior Academic Advisor in the Office of Health Sciences at Michigan State University. She previously served as chair of Department of Radiation Oncology and endowed professor in the University of Washington School of Medicine. Her specialities include advanced radiation therapy modalities; imaging and image-guided radiation; and imaging predictors of cancer treatment outcomes, for which she received two R01 grant awards; women cancers; lung cancer and neuro radiation oncology. She serves as chair of the Radiosurgery Society GRID/Lattice, Microbeam and FLASH Radiation Therapy Clinical Working Group. She has been awarded the elected Fellow of the American Association of the Advancement of Science (AAAS), Fellow of ASTRO, and the American Board of Radiology Lifetime Service Award for her contributions to research and education. She has published over 200 journal articles.

Summary:

This textbook is a comprehensive review of the physics of heterogeneous radiation and is linked, through a multidisciplinary approach, to clinical applications and biological considerations of heterogenous radiation. Fundamental principles of Spatially Fractionated Radiation Therapy (SFRT), techniques and technologies, dosimetric properties of SFRT, planning methods, documentation, standardized reporting metrics and clinical practice recommendations are comprehensively reviewed. The current status and results of clinical patient studies are presented, which have the potential to advance the management of bulky and advanced tumors. Potential biological underpinnings are reviewed that may challenge the current radiobiological understanding of radiation response and radiation therapy design parameters. Such multidisciplinary understanding is a critical foundation as the field of heterogeneous radiation rapidly advances in technological development and clinical investigation. Part of IPEM-IOP Series in Physics and Engineering in Medicine and Biology.

Contents:

part I. Biology and clinical use. 1. Introduction to the principles of spatially fractionated radiotherapy / Karl T. Butterworth, Yolanda Prezado and Kevin M. Prise

2. General principles of SFRT biology / Andrew J. Johnsrud, Samir V. Jenkins and Robert J. Griffin

3. The immunologic effects of nonuniform dose irradiation / Ariel E. Marciscano, Encouse B. Golden and Silvia C. Formenti

4. The biology of FLASH

a critical appraisal for clinical translation / Veljko Grilj and Marie-Catherine Vozenin

5. SFRT experience in multi-disease studies of voluminous and metastatic tumors / Gregory S. Alexander, Dan K. Kunaprayoon and William F. Regine

6. GRID spatially fractionated radiation therapy : definitive radiation therapy in bulky primary tumors / Majid Mohiuddin, James W. Snider and Jos�e Pe�anagar�icano

7. Lattice Radiotherapy SFRT : definitive radiation therapy in bulky primary tumors / Beatriz E. Amendola, Naipy C. Perez, Benhua Xu, Nina A Mayr, Marco A. Amendola and Xiaodong Wu

8. Proton beam spatially fractionated radiation therapy : clinical data / Ronald Chow, Minglei Kang and Charles B. Simone, II

part II. Physics of moderate dose rate SFRT. 9. GRID-collimator-based and static-field SFRT / Hualin Zhang

10. The technical aspects of 3D lattice radiation therapy (LRT) / Xiaodong Wu, Naipy C. Perez, Xiaobo Li, Beatriz E. Amendola, Georges F. Hatoum and Benhua Xu

11. Rotational arc SFRT / Xin Zhang, Jos�e Pe�anagar�icano and Eduardo G. Moros

12. Electron beam SFRT / Hajime Monzen and Mikoto Tamura

13. Proton beam spatially fractionated radiotherapy / Mingcheng Gao and Mark Pankuch

14. Radiobiological modeling and equivalent uniform dose for spatially fractionated radiation therapy / Stefan H. Bartzsch, Robert D. Stewart and Juergen Meyer

15. Spatially fractionated radiation therapy field calibration and commissioning / Michael Grams and Hualin Zhang

16. SFRT dose prescription / Nina A. Mayr, Beatriz E. Amendola, James S. Welsh, Hualin Zhang, Naipy C. Perez, Xiaodong Wu and Simon S. Lo

17. SFRT dosimetric parameters and their associations with treatment response / Sha X. Chang and Robert J. Griffin

18. Monte Carlo simulation of photon beam spatially fractionated radiotherapy / Immaculada Mart�inez-Rovira and Jos�e M Fern�andez-Varea

19. Monte Carlo simulation of proton SFRT / Tim Schneider, Ludovic De Marzi and Ram�on Ortiz

part III. Physics of microbeam, minibeam SFRT and ultra-high dose rate FLASH therapy. 20. Microbeam SFRT with photons / Valentin Djonov, Cristian Fernandez-Palomo and Paolo Pellicioli

21. Spatially fractionated radiation therapy : from photons to charged particles / Yolanda Prezado

22. Ultra-high dose-rate electron FLASH radiation therapy / Peter G. Maxim, Emil Sch�uler and Kristoffer Petersson

23. The use of synchrotrons in SFRT and FLASH therapy / Audrey Bouchet and Marine Potez

Conclusions / Charles L. Limoli, Charles B Simone II, Nina A Mayr and Hualin Zhang

Glossary of spatially fractionated and FLASH radiation therapy / Juergen Meyer, Yolanda Prezado, Hualin Zhang and Nina A. Mayr.

Notes:

"Version: 202306"--Title page verso.

Includes bibliographical references.

Title from PDF title page (viewed on July 6, 2023).

Other Format:

Print version:

ISBN:

9780750340465

9780750340458

OCLC:

1389632657

Access Restriction:

Restricted for use by site license.