Current Trends in Drug Discovery, Development and Delivery (CTD4-2022) / edited by Manikanta Murahari, Buchi N. Nalluri, and G. Chakravarthi.

Format:

Book

Contributor:

Murahari, Manikanta, editor.

Nalluri, Buchi N., editor.

Chakravarthi, G., editor.

Series:

ISSO (Series)

Issn Series

Language:

English

Subjects (All):

Drugs--Design.

Drugs.

Pharmacology.

Drug delivery systems.

Physical Description:

1 online resource (822 pages)

Edition:

First edition.

Place of Publication:

London, England : The Royal Society of Chemistry, [2024]

Summary:

This publication is based on peer-reviewed manuscripts from the 2022 Conference on Current Trends in Drug Discovery, Development and Delivery (CTD4-2022) held at KL University, India.

Contents:

COVER

CONTENTS

PART 1 COMPUTATIONAL DESIGN OF SMALL MOLECULES FOR POTENTIAL TARGETS

HIT IDENTIFICATION FROM GANODERMA LUCIDUM TO TREAT POLYCYSTIC OVARIAN SYNDROME: AN IN-SILICO APPROACH

1 INTRODUCTION

2 MATERIALS AND METHODS

3 RESULTS AND DISCUSSION

4 CONCLUSION

5 ACKNOWLEDGMENT

6 REFERENCES

FRAGMENT BASED DRUG DESIGN (FBDD) OF AN EXEMPLAR INHIBITOR AGAINST SPIKE GLYCOPROTEIN OF SARS-COV-2

2 OBJECTIVE OF THE STUDY

3 SOFTWARES/ DATABASES APPLIED

4 RESULTS AND DISCUSSION

5 CONCLUSION

6 ACKNOWLEDGMENT

7 REFERENCES

VIRTUAL SCREENING OF MILK PROTEINS OF RISPERIDONE FOR TASTE IMPROVEMENT

EXPERIMENTAL VALIDATION OF SODIUM CASEINATE BINDING BY FLUOROMETRY AND TASTE ASSESSMENT BY PALATABILITY

2 METHODS AND MATERIALS

4 CONCLUSIONS

5 ACKNOWLEDGEMENTS

N-SILICO EVALUATION OF PHYTOCHEMICALS AS POTENTIAL ANTIEPILEPTIC DRUGS

2 METHODOLOGY

5 ACKNOWLEDGEMENT

SCREENING OF PLACENTAL PROTEINS AGAINST PROTEASES FOR THEIR POTENTIAL USE IN OSTEOARTHRITIS: A COMPUTATIONAL APPROACH

2 METHODS AND RESULTS

IN SILICO ADMET PREDICTION AND MOLECULAR DOCKING STUDIES IN THE DESIGN OF NEW THERAPEUTIC AGENTS TARGETING PIM 1 KINASE

DRUG REPURPOSING FOR PRIMARY LATERAL SCLEROSIS: A MOLECULAR DYNAMIC STUDY

3 DISCUSSIONS

ARTIFICIAL NEURAL NETWORK PROCESS USED IN GLOBAL DRUG DISCOVERY AND DEVELOPMENT

1 INTRODUCTION.

2 METHODS &amp

RESULTS

3 DISCUSSION

SCREENING OF SOME NOVEL ISOXAZOLES AGAINST C. ALBICANS FOR THEIR POTENTIAL USE AS ANTIFUNGALS: A COMPUTATIONAL APPROACH

EVALUATION OF IN-SILICO AND IN-VITRO ANTHELMINTIC ACTIVITY OF HEYDOTIS ASPERA (HEYNE EX ROTH) USING PHERETIMA POSTHUMA

5 REFERENCES

IDENTIFICATION, MODELLING AND DOCKING STUDIES ON SERT LIKE MYCOBACTERIAL PROTEIN AS A POSSIBLE ANTI TB DRUG TARGET

IN SILICO DESIGN OF NATURAL COMPOUND-DERIVED NOVEL INHIBITORS AGAINST RdRP OF SARS-CoV-2

6 CONFLICT OF INTEREST

IN SILICO SCREENING, ANALYSIS AND DESIGN OF POTENTIAL INHIBITORS AGAINST RSMD FOR TREATING TUBERCULOSIS

3 RESULTS

4 DISCUSSIONS

5 CONCLUSIONS

7 CONFLICTS OF INTEREST

8 FUNDING

9 REFERENCES

TOXICITY AND BREAST CANCER RISK PREDICTION STUDIES FOR CARBAMATES: BIOINFORMATICS APPROACH

IN SILICO PHARMACOKINETIC AND PHARMACODYNAMIC SCREENING METHODS OF PHYTOL

AN ANTITUBERCULAR LEAD DISCOVERY STUDY

2 METHODS

7 REFERENCES.

PART 2 DEVELOPMENT AND VALIDATION OF DRUGS AND DOSAGE FORMS BY ANALYTICAL AND BIOANALYTICAL TECHNIQUES

DEVELOPMENT AND VALIDATION OF HPLC METHOD FOR QUANTIFICATION OF PARECOXIB IN PARECOXIB INJECTION

1. INTRODUCTION

2. MATERIALS

3. RESULTS AND DISCUSSION

4. CONCLUSION

5. ACKNOWLEDGMENT

6. REFERENCES

QUANTIFICATION OF DARIDOREXANT IN HUMAN PLASMA USING RP HPLC:A BIOANALYTICAL METHOD DEVELOPMENT AND VALIDATION

2. MATERIAL AND METHODS

5. ACKNOWLEDGEMENTS

A UV-SPECTROPHOTOMETRIC METHOD FOR SIMULTANEOUS ESTIMATION OF ABACAVIR AND LAMIVUDINE IN THEIR PHARMACEUTICAL DOSAGE FORMS

2. METHODS AND MATERIALS

5 ACKNOWLEDGMENTS

PHARMACOKINETIC PROFILE OF NOVEL CURCUMIN-METFORMIN CONJUGATE IN RATS BY LC-MS/MS

5. ACKNOWLEDGEMENT

6. ETHICAL APPROVAL

7. FUNDING

8. REFERENCES

DEVELOPMENT AND VALIDATION OF A RP-HPLC METHOD FOR THE SIMULTANEOUS DETERMINATION OF TWENTY RELATED SUBSTANCES OF SULFAMETHOXAZOLE AND TRIMETHOPRIM IN INJECTION DOSAGE FORM

2. MATERIALS AND METHODS

5. REFERENCES

A SENSITIVE AZEOTROPIC SOLVENT SCREENING HEAD SPACE GAS CHROMATOGRAPHIC METHOD FOR TERIFLUNOMIDE DRUG SUBSTANCE

5. AKNOWLEDGEMENTS

A NOVEL FOURIER TRANSFORM INFRARED SPECTROPHOTOMETRIC METHOD FOR QUANTITATIVE ANALYSIS OF IRBESARTAN AND HYDROCHLORTHIAZIDE IN FIXED DOSE FORMULATIONS

5 REFERENCES.

DEVELOPMENT AND VALIDATION OF RP-HPLC-PDA METHOD FOR THE ESTIMATION OF FLUOXETINE HYDROCHLORIDE IN BULK, MOUTH DISSOLVING FILMS AND IN DISSOLUTION SAMPLES

3. RESULTS AND DISCUSSIONS

A HIGH-PERFORMANCE LIQUID CHROMATOGRAPHIC METHOD FOR DISSOLUTION TESTING OF LURASIDONE TABLETS

3 RESULTS AND DISCUSSIONS

DEVELOPMENT AND VALIDATION OF STABILITY INDICATING RELATED SUBSTANCES METHOD FOR MONTELUKAST SODIUM AND LEVOCETIRIZINE DIHYDROCHLORIDE COMBINED TABLETS BY RP HPLC

2. METHOD DEVELOPMENT AND VALIDATION

5. RECOMMENDATION

6. ACKNOWLEDGEMENTS

7. REFERENCES

DEVELOPMENT OF RP-HPLC-PDA METHOD VALIDATION FOR THE SIMULTANEOUS ESTIMATION OF ZIDOVUDINE, LAMIVUDINE, AND NEVIRAPINE IN BULK AND DOSAGE FORMS AND IN DISSOLUTION SAMPLES

PART 3 NOVEL DRUG DELIVERY SYSTEMS

DESIGN, DEVELOPMENT AND CHARACTERIZATION OF EBERCONAZOLE PRONIOSOMES

DESIGN AND EVALUATION OF MUCOADHESIVE IN SITU LIPOSOMAL GEL FOR SUSTAINED OCULAR DELIVERY OF DIFLUPREDNATE USING TWO STEPS FACTORIAL DESIGN

2. METHODS AND RESULTS

FORMULATION AND EVALUATION OF DESONIDE LOADED NIOSOMES PREPARED BY FILM HYDRATION TECHNIQUE USING BOX-BEHNKEN DESIGN

2. METHODOLOGY

3. CONCLUSION

4. ACKNOWLEDGEMENTS

5. REFERENCES.

FORMULATION AND CHARACTERIZATION OF BILASTINE ORAL DISINTEGRATED TABLETS USING NATURAL AND SYNTHETIC SUPER DISINTEGRANTS

NANOFORMULATED EPIGALLOCATECHIN GALLATE FOR ITS POTENTIAL MANAGEMENT OF ORAL SQUAMMOUS CELL CARCINOMA

IN VIVO SKIN IRRITATION POTENTIAL OF A TOPICAL GEL LOADED WITH TEA TREE OIL NANOSPONGES

GABAPENTIN NOVEL CO-CRYSTALS: AN ATTEMPT TO ENHANCE PHYSICOCHEMICAL PARAMETERS

3 EVALUATIONS

4. RESULTS AND DISCUSSION

6 ACKNOWLEDGMENTS

8 REFERENCES

QUALITY BY DESIGN APPROACH FOR OPTIMIZATION AND DEVELOPMENT OF GASTRO-RETENTIVE HOLLOW MICROSPHERES FOR PRASUGREL

FORMULATION OF CANDISARTAN MUCOADHESIVE BUCCAL TABLETS AFTER IMPROVING THE SOLUBILITY BY SOLID DISPERSION AND INCLUSION COMPLEX METHODS.

PREPARATION &amp

EVALUATION OF ACETYLATED JACK FRUIT SEED STARCH AS A CARRIER FOR CONTROLLED RELEASE DRUG DELIVERY OF ZIDOVUDINE TABLETS

1.INTRODUCTION

3. RESULTS

PREPARATION AND CHARACTERIZATION OF MONTELUKAST SODIUM LOADED CUBOSOMAL VESICLES FOR ORAL DELIVERY USING CENTRAL COMPOSITE DESIGN

2.MATERIALS AND METHODS

3.DISCUSSION

4.CONCLUSION.

5.CONFLICTS OF INTEREST.

Notes:

Includes bibliographical references.

Description based on publisher supplied metadata and other sources.

Description based on print version record.

ISBN:

9781837671090

1837671095