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The chemical biology of carbon / Christopher T Walsh.
- Format:
- Book
- Author/Creator:
- Walsh, Christopher, author.
- Series:
- Chemical biology series ; volume 21.
- Chemical Biology Series ; volume 21
- Language:
- English
- Subjects (All):
- Carbon.
- Physical Description:
- 1 online resource (564 p.)
- Edition:
- First edition.
- Place of Publication:
- London, England : Royal Society of Chemistry, [2023]
- Summary:
- This volume examines chemical biology open to carbon-containing natural metabolites that allow both retrospective and predictive behaviours of both biosynthetic and degradative metabolism in primary and secondary pathways. The book also notes the centrality of a core set of heterocycles in metabolites and coenzyme forms of vitamins and how that chemistry enables life. The organic chemical fundamental considerations are always tied to specific metabolites and metabolic transformations. This context makes this volume not a classical organic or even bioorganic approach to organic chemistry in vivo but instead a unique analysis of how the rules and reactivities of organic chemistry underlie the organic chemistry of life.
- Contents:
- Introduction to Carbon Chemical Biology; Olefin and Alkyne Functional Groups; C-O Bond Formation and Reactivity: A Family of Related Functional Groups; Carbon-Sulfur Bonds: Adding to Functional Group Inventory; Carbon-Nitrogen Functional Groups; Purines and Pyrimidines: Essential Nitrogen Heterocycles; Carbacyclic Metabolites: Alicyclic and Aromatic Rings in Chemical Biology; Heterocycles-I; Heterocycles in Chemical Biology-II: Vitamins; Routes That Make and Break C-H and C-C Bonds In Vivo I: Carbanion Generation; Routes to Make and Break C-C Bonds II: Carbon Electrophiles; Carbon Radicals; Cascades vs Concerted Reactions; Glucose Chemical Biology; C-C Bonds in Biosynthesis: Squalene and the Sterol Biosynthetic Pathway; Chemical Biology of the Nitrogen Heterocycle Porphobilinogen in Tetrapyrrole Macrocycle Biosynthesis.
- Notes:
- Includes bibliographical references and index.
- Description based on publisher supplied metadata and other sources.
- Description based on print version record.
- Description based on print record.
- ISBN:
- 9781839169519
- 1839169516
- 9781839169502
- 1839169508
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