Biochemistry of collagens, laminins and elastin : structure, function and biomarkers / Morten Karsdal.

Format:

Book

Author/Creator:

Karsdal, Morten A., author.

Language:

English

Subjects (All):

Extracellular matrix proteins.

Biochemistry.

Biochemical markers.

Physical Description:

1 online resource (470 pages)

Edition:

Third edition.

Place of Publication:

Amsterdam : Academic Press, 2023.

Summary:

Biochemistry of Collagens, Laminins, and Elastin: Structure, Function and Biomarkers, Third Edition provides current data on key structural proteins (collagens, laminins, and elastin), reviews on how these molecules affect pathologies, and information on how selected modifications of these proteins can result in altered signaling properties of the original extracellular matrix (ECM). Further, it discusses the novel concept that an increasing number of components of the extracellular matrix harbor cryptic signaling functions with ties to endocrine function, and how this knowledge may be used to modulate various pathologies, including fibrotic disease. This new edition has been expanded and revised to incorporate recent research advances. Several new chapters explore a range of chronic diseases in which the ECM and collagens, laminin and elastin are central players in disease modulation, including new chapters on lung, skin and intestinal disease, as well as cancers. The new edition also considers emerging analytical technologies that can detect biomarkers of ECM degradation, with discussion of protein quantification and detecting aging of collagens.

Notes:

Previous edition: London: Academic Press, 2019.

Print version record.

Other Format:

Print version: Karsdal, Morten A. Biochemistry of collagens, laminins and elastin.

ISBN:

0443156182

9780443156182

OCLC:

1409430469

Access Restriction:

Restricted for use by site license.