Toxicity of atmospheric aerosols : methodologies & assays / Fobang Liu and Nga Lee Ng.

Format:

Book

Author/Creator:

Liu, Fobang, Xi'an Jiaotong University., author.

Ng, Nga Lee, Georgia Institute of Technology., author.

Contributor:

American Chemical Society.

Series:

ACS in focus, 2691-8307.

ACS in focus, 2691-8307

Language:

English

Subjects (All):

Atmospheric aerosols--Health aspects.

Atmospheric aerosols.

Aerosols--Measurement.

Aerosols.

Particulate matter--Health aspects.

Particulate matter.

Air--Pollution--Measurement.

Air.

Particulate Matter--analysis.

Medical Subjects:

Particulate Matter--analysis.

Genre:

Electronic books.

Physical Description:

1 online resource : illustrations (some color)

Place of Publication:

Washington, DC, USA : American Chemical Society, 2023.

Summary:

"Atmospheric aerosols, or particulate matter (PM), are liquid or solid particles suspended in the air. Exposure to ambient PM is associated with multiple diseases and accounts for millions of premature deaths today. Although recognized as an important public health problem, PM's toxicity and toxicological mechanisms are yet to be understood. Various methodologies and assays (i.e., procedures to determine the composition, quantity, or quality of a substance or a mixture) have been developed or employed to understand the components and characteristics of PM that best determine its toxicity. Efforts have also been spent to study the mechanisms of cellular signaling, stress, response, and physiological change, as well as complex multi-tissue effects upon PM exposure. These assays are diverse, spanning from in vitro acellular assays (i.e., chemical assays) to in vitro cellular and in vivo assays. Given that various methodologies and assays have been developed or employed, this digital primer aims to introduce the methodologies and fundamental principles used to study atmospheric aerosols' toxicity and emerging new techniques. A comprehensive literature review of the scientific findings using these methodologies and assays is not the focus of this primer. The target audiences are senior undergraduates or beginning graduate students unfamiliar with aerosol science and toxicity measurements. An introductory overview of atmospheric aerosols and the motivations to study their toxicity before a detailed discussion of methodologies and assays in the toxicity research of atmospheric aerosols is provided. Beyond this, Toxicity of Atmospheric Aerosols: Methodologies & Assays serves as an assembly of the various methodologies and assays used in the toxicity research of atmospheric aerosols, saving readers time compared to searching from scattered resources."-- Provided by publisher.

Contents:

Introduction of Atmospheric Aerosols

Motivations to Study the Toxicity of Atmospheric Aerosols

In Vitro Acellular Assays

In Vitro Cellular Assays

In Vivo Assays

Challenges and Perspectives.

Notes:

Includes bibliographical references and index.

Local Notes:

American Chemical Society, Toxicity of Atmospheric Aerosols: Methodologies and Assays eBooks - 2023 Front Files.

ISBN:

9780841299818

Access Restriction:

Restricted for use by site license.