From loss to memory : behind the discovery of synaptic pruning / Anna Huttenlocher.

Format:

Book

Author/Creator:

Huttenlocher, Anna, author.

Series:

Cambridge medicine (Series)

Cambridge medicine

Language:

English

Subjects (All):

Huttenlocher, Peter R.

Neurologists--Germany.

Neurologists.

Neurologists--United States.

Physical Description:

1 online resource (x, 149 pages) : digital, PDF file(s).

Place of Publication:

Cambridge, United Kingdom ; New York, NY : Cambridge University Press, 2023.

Summary:

How do the billions of connections between neurons in our brain change as we learn and remember? This is the story of the discovery and the discoverer of synaptic pruning, the process of synapse elimination central to making us who we are. Taking the reader from Professor Peter Huttenlocher's childhood in wartime and post-war Germany to his emigration to the US to reunite with his mother and the launch and progress of a career in medicine and research, we uncover the motivations and process of scientific discovery that led to an unexpected leap in our understanding of the human brain. Decades after the discovery, the importance of synaptic pruning to early learning, autism, schizophrenia, Alzheimer's disease and other conditions are now in the process of being uncovered.

Contents:

Discovering synaptic pruning

Else, Peters mother

Richard, Peters father, and Peters Uncle Fritz

Greiz : Kriegskinder (Children of war)

In Braubach, after the war

University of Buffalo and philosophy

Harvard Medical School

Understanding sleep and consciousness : research at NIH

Entering the cognitive revolution : neuroscience and cognitive psychology

Physician first, scientist second?

Comparative brainr egions and synapse formation

Stimulating progress on developmental brain disorders

Neurodevelopmental disorders and schizophrenia : a role for synaptic pruning?

Early childhood education

Peter and Janellen's collaboration

Microglia and the mechanisms of synaptic pruning

Looking forward : being a physician and a scientist

Parkinson's disease and Berlin

Auf Deutsch

Reflections at the end.

Notes:

Title from publisher's bibliographic system (viewed on 10 Oct 2023).

Other Format:

Print version:

ISBN:

9781009267038 (ebook)

Access Restriction:

Restricted for use by site license.