Genome-scale algorithm design : bioinformatics in the era of high-throughput sequencing / Veli Mäkinen, Djamal Belazzougui, Fabio Cunial, Alexandru I. Tomescu.

Format:

Book

Author/Creator:

Mäkinen, Veli, author.

Belazzougui, Djamal, author.

Tomescu, Alexandru I., author.

Cunial, Fabio, author.

Language:

English

Subjects (All):

Genomics.

Nucleotide sequence.

Physical Description:

1 online resource (xxiv, 444 pages) : digital, PDF file(s).

Edition:

Second edition.

Place of Publication:

Cambridge : Cambridge University Press, 2023.

Summary:

Presenting the fundamental algorithms and data structures that power bioinformatics workflows, this book covers a range of topics from the foundations of sequence analysis (alignments and hidden Markov models) to classical index structures (k-mer indexes, suffix arrays, and suffix trees), Burrows-Wheeler indexes, graph algorithms, network flows, and a number of advanced omics applications. The chapters feature numerous examples, algorithm visualizations, and exercises, providing graduate students, researchers, and practitioners with a powerful algorithmic toolkit for the applications of high-throughput sequencing. An accompanying website (www.genome-scale.info) offers supporting teaching material. The second edition strengthens the toolkit by covering minimizers and other advanced data structures and their use in emerging pangenomics approaches.

Notes:

Title from publisher's bibliographic system (viewed on 28 Sep 2023).

Other Format:

Print version:

ISBN:

9781009341257 (ebook)

Access Restriction:

Restricted for use by site license.