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Tutorials in Clinical Chemistry

Elsevier ScienceDirect eBook - Biochemistry, Genetics and Molecular Biology 2023 Available online

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Format:
Book
Author/Creator:
Hashim, Ibrahim A.
Language:
English
Subjects (All):
Clinical chemistry.
Chemistry, Clinical.
Medical Subjects:
Chemistry, Clinical.
Physical Description:
1 online resource
Place of Publication:
San Diego Elsevier 2023
Contents:
Intro
Tutorials in Clinical Chemistry
Copyright
Dedication
Contents
Preface
Acknowledgments
Abbreviations
Reference intervals
Chapter 1 Endocrine system disorders
Introduction
The thyroid gland
Structure
Function
Thyroid hormones and metabolism
Deiodinase isoenzymes
Reverse triiodothyronine (rT3)
Thyroid hormones binding proteins
Thyroid hormone resistance
Thyroid function tests (TFTs)
Thyroid stimulating hormone (TSH)
Thyroid hormones (T4 and T3)
Equilibrium dialysis methods
Total thyroxine (T4)
Free thyroxine
Total triiodothyronine (T3)
Thyroglobulin
Limitations with free home assays
Interferences
Binding proteins
Abnormalities in thyroid binding globulin (TBG)
Abnormalities in albumin levels and in binding
Familial dysalbuminemia
Limitation with TSH measurements
Autoantibodies
Antiperoxidase antibodies
Anti-TSH receptor antibodies
Heparin effect
Interfering antibodies
Biotin interference
Drugs interreference
Antigen-excess "hook-effect"
Thyroid disorders
Hyperthyroidism
T3 thyrotoxicosis
Toxic multinodular goiter
Thyroid storm
TSH adenomas
Hypothyroidism
Congenital hypothyroidism
Nonthyroidal illness
Mild hypothyroidism/mild hyperthyroidism
Subclinical hypothyroidism
Subclinical hyperthyroidism
Thyroid resistance syndrome
Organs influenced by thyroid function
Thyroid malignancy
Thyroglobulin assays
Calcitonin
TRH test
Parathyroid glands disorders
PTH measurement
Pathophysiology
Hyperparathyroidism
Hypoparathyroidism
Summary
Thyroid
Parathyroid glands
The pituitary
The pituitary gland
Anterior pituitary
Hormones and their control
Adrenocorticotrophic hormone (ACTH) (corticotrophin)7
Gonadotrophins
Growth hormone (GH)
Thyrotropin (thyroid stimulating hormone) TSH
Prolactin (PRL)
Pituitary disorders and their investigation
Anterior hyperpituitarism
Adrenocorticotrophic hormone (ACTH)
ACTH-dependent Cushing's (Cushing's disease)
Follicle stimulating hormone (FSH) and luteinizing hormone (LH)
TSH
Macroprolactin
Antigen excess (hook effect)
Anterior hypopituitarism
Adrenocorticotrophin hormone (ACTH)
Follicle stimulating hormone (FSH) and luteinizing hormone (LH)
Genetic testing
Thyrotropin-stimulating hormone (TSH)
Prolactin
Posterior pituitary hormones
Antidiuretic hormone (ADH) hypersecretion
Decreased ADH activity
Oxytocin
Hormonal measurement considerations
The adrenal gland
Structure/function
The adrenal cortex
Glucocorticoids (cortisol)
Androgens (dehydroepiandrosterone (DHEA))
Mineralocorticoids (aldosterone)
The adrenal medulla
Catecholamine synthesis and metabolism
Function
Notes:
Description based upon print version of record
Adrenal disorders
Other Format:
Print version Hashim, Ibrahim A. Tutorials in Clinical Chemistry
ISBN:
9780128229187
0128229187
OCLC:
1402815478
Access Restriction:
Restricted for use by site license

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