Liquorpheresis : Cerebrospinal Fluid Filtration to Treat CNS Conditions / by Manuel Menéndez González.

Format:

Book

Author/Creator:

Menéndez González, Manuel, author.

Language:

English

Subjects (All):

Neurology.

Critical care medicine.

Nervous system--Surgery.

Nervous system.

Intensive Care Medicine.

Neurosurgery.

Local Subjects:

Neurology.

Intensive Care Medicine.

Neurosurgery.

Physical Description:

1 online resource (vi, 68 pages)

Edition:

1st ed. 2023.

Place of Publication:

Cham : Springer Nature Switzerland : Imprint: Springer, 2023.

Summary:

This book provides an overview of emerging CSF management systems that filter or clear cerebrospinal fluid (CSF) as a therapeutic approach for several CNS conditions. While the term "liquorpheresis" most accurately refers to extracorporeal procedures that filter CSF (similar to plasmapheresis), this book covers any method based on devices that -either alone or in combination with drugs- can clear CSF or enhance its turnover, which in turn dilutes toxins. The book begins with an overview of CSF anatomy and physiology, followed by a discussion of the role of CSF clearance and flow dysfunction in various CNS conditions. The next section describes the different CSF management systems and procedures that are currently available or under development. The book then reviews the potential applications of these systems for treating subarachnoid hemorrhage, CNS infections, meningeal carcinomatosis, autoimmune encephalitis, polyradiculomyelitis, and neurodegenerative diseases. Finally, a chapter discusses future advances in liquorpheresis systems and applications. This book is intended for clinicians, neuro-researchers, academics, and students who are interested in the development and application of CSF management systems. It is also relevant to the medical device industry, particularly those that develop apheresis and CSF management devices, and the drug-delivery industry.

Contents:

Anatomy and Physiology

The four layers of meninges

The BBB

The cerebrospinal fluid (CSF) and the Interstitial fluid (ISF)

Introduction to liquorpheresis

Clearing the CSF as a therapeutic strategy in neurodegenerative diseases

Definitions of procedures, including a historical perspective

Systems and procedures

Types of procedures and systems

Classification and definitions of the different types of procedures for mechanical filtration of the CSF

The mechanism of action

The regime of usage

The implantability

The power for CSF flow

The CSF filtrating or neutralizing method

Applications and industry

Multiple sclerosis, autoimmune encephalitis, and polyradiculomyelitis

Meningeal carcinomatosis and leptomeningeal metastases

Infectious diseases

Viral encephalitis and viral myelitis

Bacterial meningoencephalitis

Fungal meningitis and fungal encephalitis

Brain aging and neurodegenerative diseases

Future advances in liquorpheresis systems and applications

New technical developments

New applications.

Other Format:

Print version: Menéndez González, Manuel Liquorpheresis

ISBN:

3-031-43482-X

OCLC:

1402228154