Virology : Principles and Applications.

Format:

Book

Author/Creator:

Carter, John B., $d 1944-

Language:

English

Subjects (All):

Virology.

Viruses.

Virus diseases.

Virus Diseases.

Medical Subjects:

Viruses.

Virus Diseases.

Physical Description:

1 online resource (396 pages)

Edition:

2nd ed.

Place of Publication:

Chichester : John Wiley & Sons, Incorporated, 2013.

Summary:

The second edition of Virology is an accessible introduction designed to enable students to understand the principles of virus structure, replication and genetics. The aim of this book is to help the reader appreciate the relevance of virology in the modern world, including the fields of vaccines, anti-viral drugs and cancer. There is also a chapter on prions. The second edition has been extensively revised and updated to reflect the many developments in virology and offers deeper insights into the subject. Newly-discovered viruses are discussed and there is an additional chapter on the influenza virus.

Contents:

Cover

Title Page

Copyright

Brief Contents

Contents

Preface to Second Edition

Preface to First Edition

Abbreviations Used in This Book

Greek Letters Used in This Book

Color Coding for Molecules

Chapter 1: Viruses and Their Importance

1.1: Viruses Are Ubiquitous on Earth

1.2: Reasons for Studying Viruses

1.3: The Nature of Viruses

1.4: The Remainder of the Book

Chapter 2: Methods Used in Virology

2.1: Introduction to Methods Used in Virology

2.2: Cultivation of Viruses

2.3: Isolation of Viruses

2.4: Centrifugation

2.5: Structural Investigations of Cells and Virions

2.6: Electrophoretic Techniques

2.7: Detection of Viruses and Virus Components

2.8: Infectivity Assays

2.9: Virus Genetics

2.10: Investigation of Protein-Protein Interactions

Chapter 3: Virus Structure

3.1: Introduction to Virus Structure

3.2: Virus Genomes

3.3: Virus Proteins

3.4: Capsids

3.5: Virion Membranes

3.6: Occlusion Bodies

3.7: Other Virion Components

Chapter 4: Virus Transmission

4.1: Introduction to Virus Transmission

4.2: Transmission of Plant Viruses

4.3: Transmission of Vertebrate Viruses

4.4: Transmission of Invertebrate Viruses

4.5: Permissive Cells

Chapter 5: Attachment and Entry of Viruses into Cells

5.1: Overview of Virus Replication

5.2: Animal Viruses

5.3: Bacteriophages

Chapter 6: Transcription, Translation, and Transport

6.1: Introduction to Transcription, Translation, and Transport

6.2: Transcription of Virus Genomes

6.3: Transcription in Eukaryotes

6.4: Translation in Eukaryotes

6.5: Transport of Molecules in Eukaryotic Cells

6.6: Transcription and Translation in Bacteria

Chapter 7: Virus Genome Replication

7.1: Overview of Virus Genome Replication.

7.2: Locations of Virus Genome Replication in Eukaryotic Cells

7.3: Initiation of Genome Replication

7.4: Polymerases

7.5: DNA Replication

7.6: Double-Stranded RNA Replication

7.7: Single-Stranded RNA Replication

7.8: Reverse Transcription

Chapter 8: Assembly and Exit of Virions from Cells

8.1: Introduction to Assembly and Exit of Virions from Cells

8.2: Nucleocapsid Assembly

8.3: Formation of Virion Membranes

8.4: Virion Exit From the Infected Cell

Chapter 9: Outcomes of Infection for the Host

9.1: Introduction to Outcomes of Infection for the Host

9.2: Factors Affecting Outcomes of Infection

9.3: Non-Productive Infections

9.4: Productive Infections

Chapter 10: Classification and Nomenclature of Viruses

10.1: History of Virus Classification and Nomenclature

10.2: Modern Virus Classification and Nomenclature

10.3: Baltimore Classification of Viruses

Chapter 11: Herpesviruses (and Other dsDNA Viruses)

11.1: Introduction to Herpesviruses

11.2: The Human Herpesviruses

11.3: The Herpesvirus Virion

11.4: HSV-1 Genome Organization

11.5: HSV-1 Replication

11.6: Latent Herpesvirus Infection

11.7: Other dsDNA Viruses

Chapter 12: Parvoviruses (and Other ssDNA Viruses)

12.1: Introduction to Parvoviruses

12.2: Examples of Parvoviruses

12.3: Parvovirus Virion

12.4: Parvovirus Replication

12.5: Other ssDNA Viruses

Chapter 13: Reoviruses (and Other dsRNA Viruses)

13.1: Introduction to Reoviruses

13.2: Rotavirus Virion

13.3: Rotavirus Replication

13.4: Other dsRNA Viruses

Chapter 14: Picornaviruses (and Other Plus-Strand RNA Viruses)

14.1: Introduction to Picornaviruses

14.2: Some Important Picornaviruses

14.3: Picornavirus Virion

14.4: Picornavirus Replication

14.5: Picornavirus Recombination.

14.6: Picornavirus Experimental Systems

14.7: Other Plus-Strand RNA Viruses

Chapter 15: Rhabdoviruses (and Other Minus-Strand RNA Viruses)

15.1: Introduction to Rhabdoviruses

15.2: Some Important Rhabdoviruses

15.3: The Rhabdovirus Virion and Genome Organization

15.4: Rhabdovirus Replication

15.5: Other Minus-Strand RNA Viruses and Viruses with Ambisense Genomes

15.6: Reverse Genetics

Chapter 16: Influenza Virus

16.1: Introduction to Influenza Viruses

16.2: The Influenza Virion

16.3: Influenza A Virus Replication

16.4: Importance of Influenza Viruses

16.5: Reverse Genetics

Chapter 17: Retroviruses

17.1: Introduction to Retroviruses

17.2: Retrovirus Virion

17.3: Retrovirus Replication

17.4: Examples of Retroviruses

17.5: Retroviruses as Gene Vectors

17.6: Endogenous Retroviruses

Chapter 18: Human Immunodeficiency Viruses

18.1: Introduction to HIV

18.2: HIV Virion

18.3: HIV Genome

18.4: HIV-1 Replication

18.5: HIV-1 Variability

18.6: Progression of HIV Infection

18.7: Prevention of HIV Transmission

Chapter 19: Hepadnaviruses (and Other Reverse-Transcribing DNA Viruses)

19.1: Introduction to Hepadnaviruses

19.2: Importance of HBV

19.3: HBV Virion

19.4: Non-Infectious Particles

19.5: Soluble Virus Protein

19.6: HBV Genome

19.7: HBV Genetic Groups

19.8: HBV Replication

19.9: Prevention and Treatment of HBV Infection

19.10: Other Reverse-Transcribing DNA Viruses

Chapter 20: Bacterial Viruses

20.1: Introduction to Bacterial Viruses (Bacteriophages)

20.2: Single-Stranded RNA Phages

20.3: Double-Stranded RNA Phages

20.4: Single-Stranded DNA Phages

20.5: Double-Stranded DNA Phages

Chapter 21: Origins and Evolution of Viruses

21.1: Introduction to Origins and Evolution of Viruses

21.2: Origins of Viruses.

21.3: Evolution of Viruses

Chapter 22: Emerging Viruses

22.1: Introduction to Emerging Viruses

22.2: Viruses in New Host Species

22.3: Viruses in New Areas

22.4: Viruses in New Host Species and in New Areas

22.5: New viruses

22.6: Recently Discovered Viruses

22.7: Re-Emerging Viruses

22.8: Virus Surveillance

22.9: Dealing with Outbreaks

Chapter 23: Viruses and Cancer

23.1: Introduction to Viruses and Cancer

23.2: Papillomavirus-Linked Cancers

23.3: Polyomavirus-Linked Cancers

23.4: Epstein-Barr Virus-Linked Cancers

23.5: Kaposi's Sarcoma

23.6: Adult T Cell Leukemia

23.7: Hepatocellular Carcinoma

23.8: Virus-Associated Cancers in Animals

23.9: Cell Lines Derived From Virus-Associated Cancers

23.10: How Do Viruses Cause Cancer?

23.11: Prevention of Virus-Induced Cancers

Chapter 24: Survival of Infectivity

24.1: Preservation of Virus Infectivity

24.2: Destruction of Virus Infectivity

24.3: Inactivation Targets in Virions

24.4: Inactivation Kinetics

24.5: Agents that Inactivate Virus Infectivity

Chapter 25: Virus Vaccines

25.1: Introduction to Virus Vaccines

25.2: Live Attenuated Virus Vaccines

25.3: Inactivated Virus Vaccines

25.4: Virion Subunit Vaccines

25.5: Live Recombinant Virus Vaccines

25.6: Mass-Production of Viruses for Vaccines

25.7: Virus-Like Particles

25.8: Synthetic Peptide Vaccines

25.9: DNA Vaccines

25.10: Storage and Transport of Vaccines

Chapter 26: Anti-viral Drugs

26.1: Introduction to Anti-viral Drugs

26.2: Development of Anti-viral Drugs

26.3: Examples of Anti-viral Drugs

26.4: Drug Resistance

26.5: Anti-viral Drug Research

Chapter 27: Prions

27.1: Introduction to Prions

27.2: Transmissible Spongiform Encephalopathies

27.3: The Nature of Prions

27.4: Prion Diseases.

27.5: Prion Strains

27.6: Prion Transmission

27.7: The Protein-Only Hypothesis

Virologists' Vocabulary

Index.

Notes:

Description based on publisher supplied metadata and other sources.

Other Format:

Print version: Carter, John Virology: Principles and Applications

ISBN:

9781118629796

1118629795

9781118629802

1118629809