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Applications of Stem Cells and derived Exosomes in Neurodegenerative Disorders / edited by Sadaf Jahan, Arif Jamal Siddiqui.

Springer Nature - Springer Biomedical and Life Sciences eBooks 2023 English International Available online

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Format:
Book
Contributor:
Jahan, Sadaf, editor.
Siddiqui, Arif Jamal, editor.
Language:
English
Subjects (All):
Neurosciences.
Developmental biology.
Nervous system--Diseases.
Nervous system.
Neuroscience.
Developmental Biology and Stem Cells.
Neurological Disorders.
Local Subjects:
Neuroscience.
Developmental Biology and Stem Cells.
Neurological Disorders.
Physical Description:
1 online resource (xiii, 327 pages) : illustrations
Edition:
1st ed. 2023.
Place of Publication:
Singapore : Springer Nature Singapore : Imprint: Springer, 2023.
Summary:
This book explores the therapeutic approaches of stem cells and stem cell-derived exosomes against neurodegenerative disorders (NDDs). The initial chapters introduce different neurodegenerative diseases and discuss the mechanistic aspects of their progression. The subsequent chapters cover strategies for the isolation, characterization, and differentiation of stem cells. In turn, the book reviews the protective role of stem cells against neurological disorders and examines regenerative approaches to treat neurological diseases using mesenchymal stem cells. The book also presents induced pluripotent stem cell (iPSC) technology for cellular therapy, drug screening, and in-vitro modeling of neurodegenerative diseases. Lastly, the book discusses the role of stem cells and derived exosomes as a novel therapeutic agent against Alzheimer's and Parkinson's disease and in associated signaling molecules involved in neuroprotection. This book is an invaluable source for researchers working towards understanding the potential of stem cell therapy in neurodegenerative disorders.
Contents:
Chapter 1. History, origin and types of neurological disorders
Chapter 2. Mechanistic approach involved in the progression of Neurodegenerative disorders
Chapter 3. Isolation, characterization and differentiation of stem cells
Chapter 4. Role of Stem cells as a protective agent against neurological complications
Chapter 5. Mesenchymal stem cells and their application against neurodegenerative disorders
Chapter 6. iPSCs and their role in amelioration of neurodegenerative disorders
Chapter 7. Isolation, characterization and detailed history of exosomes derived from stem cells and their epigenetic biology
Chapter 8. Stem cells vs exosomes: promising therapeutic approach and biomarkers agent against neurodegenerative disorders
Chapter 9. Role of stem cells and derived exosomes as a novel therapeutic agent against neuroinflammation and stroke
Chapter 10. Role of stem cells and derived exosomes as a novel therapeutic agent against Alzheimer’s and Parkinson's disease
Chapter 11. Role of stem cells and derived exosomes and associated signalling molecules involved in neuroprotection
Chapter 12. Exosome as nanoparticles against neurodegenerative disorders.
Notes:
Includes bibliographical references.
Other Format:
Print version: Jahan, Sadaf Applications of Stem Cells and Derived Exosomes in Neurodegenerative Disorders
ISBN:
981-9938-48-1
OCLC:
1396818325

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